DUSP1

Gene Symbol	DUSP1
Entrez Gene	1843
Alt Symbol	CL100, HVH1, MKP-1, MKP1, PTPN10
Species	Human
Gene Type	protein-coding
Description	dual specificity phosphatase 1
Other Description	MAP kinase phosphatase 1|dual specificity protein phosphatase 1|dual specificity protein phosphatase hVH1|mitogen-activated protein kinase phosphatase 1|protein-tyrosine phosphatase CL100|serine/threonine specific protein phosphatase
Swissprots	Q2V508 D3DQL9 P28562
Accessions	ABB96250 CAK32189 CBX47580 EAW61425 EAW61426 P28562 AA843403 AJ227912 AK298047 BAG60344 AK298658 BAG60826 AK299391 BAG61376 AK300487 BAG62202 AK304475 BAG65288 AK316321 BAH14692 BC022463 AAH22463 X68277 CAA48338 NM_004417 NP_004408
Function	Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle. {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000250}.
Tissue Specificity	Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney. {ECO:0000269|PubMed:8106404}.
Top Pathways	MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DUSP1 peptide - ab156310 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human DUSP1 full length protein - ab114331 from Abcam Category Protein Source Wheat germ Species Human

Human DUSP1 peptide - ab45454 from Abcam Category Peptide Species Human

Human DUSP1 protein fragment - ab152347 from Abcam Category Protein Source Wheat germ Species Human

MKP-1 / DUSP1 Antibody Blocking Peptide - LS-E25251 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MKP-1 / DUSP1 Antibody Blocking Peptide - LS-E9599 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MKP-1/DUSP1 Protein - H00001843-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MKP-1/DUSP1 Recombinant Protein - H00001843-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

MKP-1/DUSP1 Peptide - P3318 from Novus Biologicals Category Peptide Species Human

MKP-1/DUSP1 Peptide - P3317 from Novus Biologicals Category Peptide Species Human

DUSP1-Antibody-C-term-Blocking-Peptide - BP8470b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DUSP1-Antibody-N-term-Blocking-Peptide - BP8470a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DUSP1 Blocking Peptide - abx062096 from Abbexa Category Peptide Species Human, Bovine, Chicken, Rabbit, Sheep

DUSP1 Peptide - AC21-0078-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

DUSP1 / MKP1 - H00001843-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DUSP1 / MKP1 - H00001843-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DUSP1 / MKP1 - H00001843-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DUSP1 / MKP1 - H00001843-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DUSP1 Peptide - 45-503P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat

Recombinant Human DUSP1, His-tagged - DUSP1-852H from Creative Biomart Category Protein Source E.Coli.

Recombinant Human DUSP1 - DUSP1-28071TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Dual Specificity Phosphatase 1 (DUSP1) - RPC902Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Dual Specificity Phosphatase 1 (DUSP1) - RPC902Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Dual Specificity Phosphatase 1 (DUSP1) - RPC902Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

MKP-1/CL100 Protein, active, 500 units - 14-391 from EMD Millipore Category Protein Source expressed in E. coli

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