DUSP1

Gene Symbol	DUSP1
Entrez Gene	1843
Alt Symbol	CL100, HVH1, MKP-1, MKP1, PTPN10
Species	Human
Gene Type	protein-coding
Description	dual specificity phosphatase 1
Other Description	MAP kinase phosphatase 1|dual specificity protein phosphatase 1|dual specificity protein phosphatase hVH1|mitogen-activated protein kinase phosphatase 1|protein-tyrosine phosphatase CL100|serine/threonine specific protein phosphatase
Swissprots	Q2V508 D3DQL9 P28562
Accessions	ABB96250 CAK32189 CBX47580 EAW61425 EAW61426 P28562 AA843403 AJ227912 AK298047 BAG60344 AK298658 BAG60826 AK299391 BAG61376 AK300487 BAG62202 AK304475 BAG65288 AK316321 BAH14692 BC022463 AAH22463 X68277 CAA48338 NM_004417 NP_004408
Function	Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle. {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000250}.
Tissue Specificity	Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney. {ECO:0000269|PubMed:8106404}.
Top Pathways	MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MKP-1 CRISPR/Cas9 KO Plasmid (h) - sc-400243 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MKP-1 HDR Plasmid (h) - sc-400243-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MKP-1 Double Nickase Plasmid (h) - sc-400243-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MKP-1 Double Nickase Plasmid (h2) - sc-400243-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MKP-1 CRISPR Activation Plasmid (h) - sc-400243-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MKP-1 CRISPR Activation Plasmid (h2) - sc-400243-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MKP-1 Lentiviral Activation Particles (h) - sc-400243-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MKP-1 Lentiviral Activation Particles (h2) - sc-400243-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MKP-1 siRNA (h) - sc-35937 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MKP-1 shRNA Plasmid (h) - sc-35937-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MKP-1 shRNA (h) Lentiviral Particles - sc-35937-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MKP-1 siRNA (h2) - sc-44312 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MKP-1 shRNA Plasmid (h2) - sc-44312-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MKP-1 shRNA (h2) Lentiviral Particles - sc-44312-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MKP-1/DUSP1 RNAi - H00001843-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU016821 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® Human Phosphatase - SIHP0088 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0090 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0089 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN2217 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2217 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12248 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr12248

DUSP1 siRNA (Human) - CRH1291 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

DUSP1 - MBS8221956 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

MKP-1 CRISPR/Cas9 KO Plasmid (h2) - sc-400243-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

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