Gene Symbol | KAT8 |
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Entrez Gene | 84148 |
Alt Symbol | MOF, MYST1, ZC2HC8, hMOF |
Species | Human |
Gene Type | protein-coding |
Description | K(lysine) acetyltransferase 8 |
Other Description | MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1|MYST histone acetyltransferase 1|MYST-1|histone acetyltransferase KAT8|histone acetyltransferase MYST1|lysine acetyltransferase 8|ortholog of Drosophila males absent on the first (MOF)|probable histone acetyltransferase MYST1 |
Swissprots | Q9NR35 A8K4Z1 Q8WZ14 Q8WYB4 Q659G0 G5E9P2 Q8IY59 Q9H7Z6 Q9HAC5 Q7LC17 |
Accessions | EAW52157 EAW52158 Q9H7Z6 AA682878 AF217501 AAL56648 AF260665 AAF72665 AF289578 AAL55762 AK021872 BAB13924 AK024102 BAB14827 AK225660 AK291106 BAF83795 AL050395 CAH56416 BC037773 AAH37773 BP342476 CD364543 HG507946 XM_011545969 XP_011544271 XM_011545970 XP_011544272 XM_011545971 XP_011544273 NM_032188 NP_115564 NM_182958 NP_892003 |
Function | Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex. Can also acetylate TP53/p53 at 'Lys-120'. {ECO:0000269|PubMed:12397079, ECO:0000269|PubMed:15923642, ECO:0000269|PubMed:20018852, ECO:0000269|PubMed:21217699, ECO:0000269|PubMed:22020126, ECO:0000269|PubMed:22547026}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10786633, ECO:0000269|PubMed:20018852}. Chromosome {ECO:0000250}. |
Rabbit anti-MOF/MYST1 Antibody, Affinity Purified - PLA0161 from Sigma-Aldrich
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Histone acetyltransferase KAT8, KAT8, Human, ELISA Kit - E2934h from ARP American Research Products
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Rat MYST1 ELISA Kit (Custom ELISA) - LS-F19808 from LifeSpan Bioscience
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Mouse MYST1 ELISA Kit (Custom ELISA) - LS-F19809 from LifeSpan Bioscience
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Histone acetyltransferase KAT8, ELISA Kit - MBS288532 from MyBioSource
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Human Histone acetyltransferase KAT8 ELISA Kit - abx251593 from Abbexa
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Human MYST1 ELISA Kit (Competitive EIA) - LS-F13283 from LifeSpan Bioscience
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Histone acetyltransferase KAT8, ELISA Kit - MBS288241 from MyBioSource
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Human Histone acetyltransferase KAT8 ELISA Kit - EKE53461 from Biomatik
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KAT8 - EKH4494 from Nordic BioSite
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KAT8 ELISA Kit (Human) (OKEH01680) - OKEH01680 from Aviva Systems Biology
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Human KAT8 ELISA Kit - E018743 from Biobool
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Human MYST1 ELISA Kit - E030843 from Biobool
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Human Histone acetyltransferase KAT8 ELISA Kit - EK4556 from Signalway Antibody
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Human Probable histone acetyltransferase MYST1 (MYST1) ELISA Kit - AE31874HU from ARP American Research Products
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Histone acetyltransferase KAT8, ELISA Kit - MBS9428382 from MyBioSource
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Histone acetyltransferase KAT8, ELISA Kit - MBS2887374 from MyBioSource
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Human MYST1 ELISA Kit (Sandwich ELISA) - LS-F33934 from LifeSpan Bioscience
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