Gene Symbol | KAT8 |
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Entrez Gene | 84148 |
Alt Symbol | MOF, MYST1, ZC2HC8, hMOF |
Species | Human |
Gene Type | protein-coding |
Description | K(lysine) acetyltransferase 8 |
Other Description | MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1|MYST histone acetyltransferase 1|MYST-1|histone acetyltransferase KAT8|histone acetyltransferase MYST1|lysine acetyltransferase 8|ortholog of Drosophila males absent on the first (MOF)|probable histone acetyltransferase MYST1 |
Swissprots | Q9NR35 A8K4Z1 Q8WZ14 Q8WYB4 Q659G0 G5E9P2 Q8IY59 Q9H7Z6 Q9HAC5 Q7LC17 |
Accessions | EAW52157 EAW52158 Q9H7Z6 AA682878 AF217501 AAL56648 AF260665 AAF72665 AF289578 AAL55762 AK021872 BAB13924 AK024102 BAB14827 AK225660 AK291106 BAF83795 AL050395 CAH56416 BC037773 AAH37773 BP342476 CD364543 HG507946 XM_011545969 XP_011544271 XM_011545970 XP_011544272 XM_011545971 XP_011544273 NM_032188 NP_115564 NM_182958 NP_892003 |
Function | Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex. Can also acetylate TP53/p53 at 'Lys-120'. {ECO:0000269|PubMed:12397079, ECO:0000269|PubMed:15923642, ECO:0000269|PubMed:20018852, ECO:0000269|PubMed:21217699, ECO:0000269|PubMed:22020126, ECO:0000269|PubMed:22547026}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10786633, ECO:0000269|PubMed:20018852}. Chromosome {ECO:0000250}. |
Human KAT8 / MYST1 / MOF full length protein - ab125660 from Abcam
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Human KAT8 / MYST1 / MOF full length protein - ab153548 from Abcam
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Human KAT8 / MYST1 / MOF peptide - ab98900 from Abcam
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MYST1 Antibody Blocking Peptide - LS-E794 from LifeSpan Bioscience
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MYST1 Antibody Blocking Peptide - LS-E17781 from LifeSpan Bioscience
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Recombinant Human MYST1 Protein - H00084148-P01 from Novus Biologicals
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MYST1 Peptide - P0235 from Novus Biologicals
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HMOFMYST1-Antibody-C-term-Blocking-Peptide - BP1114b from Abgent, a WuXi AppTec company
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MYST1 Blocking Peptide - 33R-5607 from Fitzgerald
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MYST1 - H00084148-P01-10 from Acris Antibodies
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MYST1 - H00084148-P01-25 from Acris Antibodies
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MOF fusion protein - Ag4978 from Proteintech Group
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MOF fusion protein - Ag4802 from Proteintech Group
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Recombinant Human K(Lysine) Acetyltransferase 8, GST-tagged - KAT8-1602H from Creative Biomart
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Recombinant Human KAT8 , GST-tagged - KAT8-6957H from Creative Biomart
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KAT8 (MYST1) protein-GST fusion - 009-001-S29 from Rockland Immunochemicals Inc
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KAT8 (MYST1) protein-GST fusion - 009-001-S29S from Rockland Immunochemicals Inc
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Recombinant Human Histone acetyltransferase KAT8(KAT8) - CSB-YP862038HU CSB-EP862038HU CSB-BP862038HU CSB-MP862038HU from Cusabio
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HAT-1, Peptide - MBS843994 from MyBioSource
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KAT8 Peptide, Human - M34GP07899H from Creative Peptides
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MYST1 Recombinant Protein Antigen - NBP2-56864PEP from Novus Biologicals
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Histone acetyltransferase KAT8 (KAT8), Recombinant Protein - MBS1403962 from MyBioSource
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KAT8 (MYST1), Recombinant Protein - MBS515341 from MyBioSource
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