BCL2L1

Gene Symbol	BCL2L1
Entrez Gene	598
Alt Symbol	BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS
Species	Human
Gene Type	protein-coding
Description	BCL2-like 1
Other Description	apoptosis regulator Bcl-X|bcl-2-like protein 1|protein phosphatase 1, regulatory subunit 52
Swissprots	Q92976 Q5CZ89 Q5TE65 E1P5L6 Q07817
Accessions	AAB17354 BAA06406 CAT03369 CAT03400 CBX47501 CBX47502 EAW76424 EAW76425 EAW76426 EAW76427 EAW76428 EAW76429 Q07817 AK290968 BAF83657 AY263335 AAP22027 AY263336 AAP22028 AY263337 AAP22029 BC019307 AAH19307 BT007208 AAP35872 BX647525 CR936637 CAI56777 DQ893461 ABM84387 DQ896311 ABM87310 Z23115 CAA80661 Z23116 CAA80662 XM_005260486 XP_005260543 XM_005260487 XP_005260544 XM_011528960 XP_011527262 XM_011528961 XP_011527263 XM_011528962 XP_011527264 XM_011528963 XP_011527265 XM_011528964 XP_011527266 XM_011528965 XP_011527267 XM_011528966 XP_011527268 XR_936599 NM_001191 NP_001182 NM_138578 NP_612815
Function	Isoform Bcl-X(S) promotes apoptosis.
Subcellular Location	Isoform Bcl-X(L): Mitochondrion inner membrane {ECO:0000250}. Mitochondrion outer membrane {ECO:0000250}. Mitochondrion matrix {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=After neuronal stimulation, translocates from cytosol to synaptic vesicle and mitochondrion membrane in a calmodulin-dependent manner (By similarity). Localizes to the centrosome when phosphorylated at Ser-49. {ECO:0000250}.
Tissue Specificity	Bcl-X(S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-X(L) is found in tissues containing long-lived postmitotic cells, such as adult brain.
Top Pathways	Apoptosis, Toxoplasmosis, Pancreatic cancer, HTLV-I infection, Amyotrophic lateral sclerosis (ALS)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BCL2L1-Over-expression-Lysate - LY11011a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

Bcl-2-like 1 Lysate(Denatured) - H00000598-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

BCL2L1 293 Cell Lysate - 402916 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

BCL2L1 293 Cell Lysate - 409404 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Bcl-xL Overexpression Lysate (Denatured) - H00000598-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Bcl-xL Overexpression Lysate (Native) - NBL1-07946 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Bcl-xL Overexpression Lysate (Native) - NBP2-08227 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Bcl-x (h): 293T Lysate - sc-159338 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

BCL2L1 Over-expression Lysate Product - GWB-D19503 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

BCL2L1 Over-expression Lysate Product - GWB-C5E262 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Panoply™ Human BCL2L1 Knockdown Stable Cell Line - CSC-DC001372 from Creative biogene Category Cell Line Species Human

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