BCL2L1

Gene Symbol BCL2L1
Entrez Gene 598
Alt Symbol BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS
Species Human
Gene Type protein-coding
Description BCL2-like 1
Other Description apoptosis regulator Bcl-X|bcl-2-like protein 1|protein phosphatase 1, regulatory subunit 52
Swissprots Q92976 Q5CZ89 Q5TE65 E1P5L6 Q07817
Accessions AAB17354 BAA06406 CAT03369 CAT03400 CBX47501 CBX47502 EAW76424 EAW76425 EAW76426 EAW76427 EAW76428 EAW76429 Q07817 AK290968 BAF83657 AY263335 AAP22027 AY263336 AAP22028 AY263337 AAP22029 BC019307 AAH19307 BT007208 AAP35872 BX647525 CR936637 CAI56777 DQ893461 ABM84387 DQ896311 ABM87310 Z23115 CAA80661 Z23116 CAA80662 XM_005260486 XP_005260543 XM_005260487 XP_005260544 XM_011528960 XP_011527262 XM_011528961 XP_011527263 XM_011528962 XP_011527264 XM_011528963 XP_011527265 XM_011528964 XP_011527266 XM_011528965 XP_011527267 XM_011528966 XP_011527268 XR_936599 NM_001191 NP_001182 NM_138578 NP_612815
Function Isoform Bcl-X(S) promotes apoptosis.
Subcellular Location Isoform Bcl-X(L): Mitochondrion inner membrane {ECO:0000250}. Mitochondrion outer membrane {ECO:0000250}. Mitochondrion matrix {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=After neuronal stimulation, translocates from cytosol to synaptic vesicle and mitochondrion membrane in a calmodulin-dependent manner (By similarity). Localizes to the centrosome when phosphorylated at Ser-49. {ECO:0000250}.
Tissue Specificity Bcl-X(S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-X(L) is found in tissues containing long-lived postmitotic cells, such as adult brain.
Top Pathways Apoptosis, Toxoplasmosis, Pancreatic cancer, HTLV-I infection, Amyotrophic lateral sclerosis (ALS)

Human-BCL2L1-cDNA-Clone - DC04819 from Abgent, a WuXi AppTec company

Prices $314.55
Sizes 10 µg
Species Human
Accession BC019307

BCL2L1 - CL01222H01 from Elabscience

Species Human
Accession NM_001191.2

BCL2L1 - CL01222H02 from Elabscience

Species Human
Accession NM_138578.1

Human BCL2L1 ORF clone(NM_138578.1) - CDCL182832 from Creative biogene

Species Human

Human BCL2L1 ORF clone (NM_001191.2) - CDCR034106 from Creative biogene

Species Human

Human BCL2L1 ORF Clone (BC019307) - CDCS409235 from Creative biogene

Species Human
Accession Q07817

Human BCL2L1 cDNA Clone(NM_138578.1) - CDFG008180 from Creative biogene

Species Human

Human BCL2L1 cDNA Clone(NM_001191.2) - CDFH001718 from Creative biogene

Species Human

Human BCL2 gene - orb91039 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human
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