MYDGF

Gene Symbol	MYDGF
Entrez Gene	56005
Alt Symbol	C19orf10, EUROIMAGE1875335, IL25, IL27, IL27w, R33729_1, SF20
Species	Human
Gene Type	protein-coding
Description	myeloid-derived growth factor
Other Description	UPF0556 protein C19orf10|interleukin 25|interleukin 27 working designation|interleukin-25|stromal cell-derived growth factor SF20
Swissprots	Q9NP69 O75256 Q969H8 O75272 Q9BTK7 D6W628
Accessions	AAC27824 AAC33800 EAW69202 EAW69203 Q969H8 AF282264 AK098829 AL365373 CAB96947 AL365374 CAB96948 BC003639 AAH03639 BC010129 AAH10129 BC014655 AAH14655 BG484758 NM_019107 NP_061980
Function	Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis (PubMed:25581518). {ECO:0000250|UniProtKB:Q9CPT4, ECO:0000269|PubMed:25581518}.
Subcellular Location	Secreted {ECO:0000269|PubMed:17362502, ECO:0000269|PubMed:25581518}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000269|PubMed:17362502}. Note=Secreted into blood plasma. {ECO:0000269|PubMed:25581518}.
Tissue Specificity	Expressed in bone marrow cells (PubMed:25581518). Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties (PubMed:17362502). {ECO:0000269|PubMed:17362502, ECO:0000269|PubMed:25581518}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active mouse SF20 full length protein - ab191759 from Abcam Category Protein Prices $192.00 Sizes 10 µg Source E. coli Species Mouse

Human SF20 full length protein - ab185412 from Abcam Category Protein Source E. coli Species Human

Human SF20 full length protein - ab86915 from Abcam Category Protein Source E. coli Species Human

Mouse SF20 full length protein - ab54228 from Abcam Category Protein Source E. coli Species Mouse

MYDGF / SF20 Antibody Blocking Peptide - LS-E23329 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MYDGF / SF20 Antibody Blocking Peptide - LS-E23330 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IL27 Antibody Blocking Peptide - LS-E3085 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IL27 Antibody Blocking Peptide - LS-E30233 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

IL27 Antibody Blocking Peptide - LS-E30234 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

IL27 Antibody Blocking Peptide - LS-E22227 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IL27 Antibody Blocking Peptide - LS-E6544 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human IL-27 Protein - H00246778-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human IL-27 Protein - H00246778-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

IL25 Recombinant Protein - H00056005-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

IL25 Recombinant Protein - H00056005-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human IL25 Protein - NBC1-22603 from Novus Biologicals Category Protein Prices $249.00, $549.00 Sizes 100 µg, 500 µg Species Human

IL-27 Peptide - NBP1-76412PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

IL-27 Blocking Peptide - NBP1-76698PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

IL-27 Protein - NBP1-42907 from Novus Biologicals Category Protein Prices $2,099.00 Sizes 100 µg Species Human

SF20 Protein (OPPA02224) - OPPA02224 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 10 µg Source E. Coli

Mouse SF20 protein - orb82813 from Biorbyt Category Protein Prices $2,873.00 Sizes 1 mg Source E.coli

Human C19orf10 protein - orb180291 from Biorbyt Category Protein Prices $204.00, $323.00, $1,411.00, $1,981.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human C19ORF10 (Fc Tag) protein - orb232309 from Biorbyt Category Protein Prices $434.00, $893.00 Sizes 10 μg, 50 μg Species Human

Human Chromosome 19 Open Reading Frame 10 protein - orb80602 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 10 μg, 50 μg Source E.coli

Human C19ORF10 (His Tag) protein - orb232310 from Biorbyt Category Protein Prices $434.00, $893.00 Sizes 10 μg, 50 μg Species Human

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