TUB

Gene Symbol	TUB
Entrez Gene	7275
Alt Symbol	RDOB, rd5
Species	Human
Gene Type	protein-coding
Description	tubby bipartite transcription factor
Other Description	tubby homolog|tubby homologue|tubby protein homolog
Swissprots	P50607 Q6B007 O00293 D3DQU4
Accessions	CAC14586 CAC39298 EAW68632 EAW68633 EAW68634 P50607 AB209618 BAD92855 AK293528 BAG57010 BC036400 BC075031 AAH75031 BC075032 AAH75032 BM992151 EU446711 ABZ92240 U54644 AAB53494 U82467 AAB53699 XM_005253109 XP_005253166 XM_011520344 XP_011518646 NM_003320 NP_003311 NM_177972 NP_813977
Function	Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight (By similarity). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages. {ECO:0000250, ECO:0000269|PubMed:19837063}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Secreted {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Binds phospholipid and is anchored to the plasma membrane through binding phosphatidylinositol 4,5-bisphosphate. Is released upon activation of phospholipase C. Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha. Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity). {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TUB 1 protein fragment - ab159758 from Abcam Category Protein Source Wheat germ Species Human

Human Tubby peptide - ab47529 from Abcam Category Peptide

TUB / Tubby Antibody Blocking Peptide - LS-E11822 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Tubby Protein - H00007275-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TUB (Tubby protein homolog) - H00007275-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TUB (Tubby protein homolog) - H00007275-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TUB fusion protein - ag12354 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Tubby protein homolog(TUB) - CSB-YP025305HU CSB-EP025305HU CSB-BP025305HU CSB-MP025305HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TUB (Tubby protein homolog) (transcript variant 2) - TP314538 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Tubby Recombinant Protein Antigen - NBP1-87824PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TUB Peptide, Human - M34GP16842H from Creative Peptides Category Peptide Source Synthetic. Species Human

Tubby Recombinant Protein Antigen - NBP2-48924PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

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