TUB

Gene Symbol TUB
Entrez Gene 7275
Alt Symbol RDOB, rd5
Species Human
Gene Type protein-coding
Description tubby bipartite transcription factor
Other Description tubby homolog|tubby homologue|tubby protein homolog
Swissprots P50607 Q6B007 O00293 D3DQU4
Accessions CAC14586 CAC39298 EAW68632 EAW68633 EAW68634 P50607 AB209618 BAD92855 AK293528 BAG57010 BC036400 BC075031 AAH75031 BC075032 AAH75032 BM992151 EU446711 ABZ92240 U54644 AAB53494 U82467 AAB53699 XM_005253109 XP_005253166 XM_011520344 XP_011518646 NM_003320 NP_003311 NM_177972 NP_813977
Function Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight (By similarity). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages. {ECO:0000250, ECO:0000269|PubMed:19837063}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Secreted {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Binds phospholipid and is anchored to the plasma membrane through binding phosphatidylinositol 4,5-bisphosphate. Is released upon activation of phospholipase C. Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha. Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity). {ECO:0000250}.

Tub CRISPR/Cas9 KO Plasmid (h) - sc-404280 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tub HDR Plasmid (h) - sc-404280-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tub Double Nickase Plasmid (h) - sc-404280-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tub Double Nickase Plasmid (h2) - sc-404280-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tub CRISPR Activation Plasmid (h) - sc-404280-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tub CRISPR Activation Plasmid (h2) - sc-404280-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tub Lentiviral Activation Particles (h) - sc-404280-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tub Lentiviral Activation Particles (h2) - sc-404280-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Tub siRNA (h) - sc-44176 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Tub shRNA Plasmid (h) - sc-44176-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Tub shRNA (h) Lentiviral Particles - sc-44176-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Tubby RNAi - H00007275-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU134051 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22251 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22251 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TUB siRNA (Human) - CRH4973 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Tubby RNAi - H00007275-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

TUB - MBS8200572 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TUB (NM_177972.2) - SHH437572 from Creative biogene

Category siRNA
Species Reactivities Human

Human TUB siRNA - orb265475 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TUB shRNA Plasmid (Human) - CHH4973 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TUB miRNA 3'UTR clone - MiUTR4H-TG09498 from Creative biogene

Species Reactivities Human
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