PTPN14

Gene Symbol	PTPN14
Entrez Gene	5784
Alt Symbol	PEZ, PTP36
Species	Human
Gene Type	protein-coding
Description	protein tyrosine phosphatase, non-receptor type 14
Other Description	cytoskeletal-associated protein tyrosine phosphatase|protein-tyrosine phosphatase pez|tyrosine-protein phosphatase non-receptor type 14
Swissprots	Q5VSI0 Q15678
Accessions	ADN23589 EAW93351 Q15678 AF086517 AK056963 AK090596 AK291641 BAF84330 AK298120 BAG60402 AW192897 BC017300 AAH17300 BC101754 AAI01755 BC104803 AAI04804 BX538306 DA738908 HG493205 HQ116786 ADN23590 X82676 CAA57993 XR_247032 NM_005401 NP_005392
Function	Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell- matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial- mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor. {ECO:0000269|PubMed:10934049, ECO:0000269|PubMed:12808048, ECO:0000269|PubMed:17893246, ECO:0000269|PubMed:20826270, ECO:0000269|PubMed:22233626, ECO:0000269|PubMed:22525271, ECO:0000269|PubMed:22948661}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus. Note=Translocation into the nucleus is associated with induction of cell proliferation. Partially colocalized with actin filaments at the plasma membrane.
Tissue Specificity	Ubiquitous.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Active human PTPD2 protein fragment - ab42582 from Abcam Category Protein Prices $284.00 Sizes 20 µg Source E. coli Species Human

PTPD2 peptide - ab12577 from Abcam Category Peptide

PTPD2 peptide - ab12578 from Abcam Category Peptide

PTPN14 / PEZ Antibody Blocking Peptide - LS-E3607 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PTPN14-Antibody-C-term-Blocking-Peptide - BP14810b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PTPN14 fusion protein - Ag12679 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

PTPN14 fusion protein - Ag12571 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

PTP-D2/PTPN14, Active Human Recombinant Protein - GWB-PS65D2 from Genway Biotech Category Protein Prices $353.00 Sizes 20 µg Species Human

Recombinant Human PTPN14, His-tagged - PTPN14-2055H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human PTPN14, GST-tagged - PTPN14-454H from Creative Biomart Category Protein Source E.Coli.

Recombinant Human Tyrosine-protein phosphatase non-receptor type 14(PTPN14) ,par - CSB-YP623010HU CSB-EP623010HU CSB-BP623010HU CSB-MP623010HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Protein Tyrosine Phosphatase, Non Receptor Type 14 (PTPN14) - RPD594Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

PTPN14/PTPD2 Recombinant Protein Antigen - NBP2-38712PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PTPD2-Antibody-N-term-Blocking-Peptide - BP8425a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PTPN14 Peptide, Human - M34GP12698H from Creative Peptides Category Peptide Source Synthetic. Species Human

Protein Tyrosine Phosphatase, Non Receptor Type 14 (PTPN14), Recombinant Protein - MBS2086830 from MyBioSource Category Protein Prices $140.00, $260.00, $400.00 Sizes 10 µg, 50 µg, 100 µg Source E Coli Species Human

Protein Tyrosine Phosphatase, Non-receptor Type 14, catalytic domain, Recombinant Protein - MBS636991 from MyBioSource Category Protein Prices $565.00 Sizes 20 µg Source Recombinant, Human from E Coli Species Human

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