PTPN14

Gene Symbol PTPN14
Entrez Gene 5784
Alt Symbol PEZ, PTP36
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase, non-receptor type 14
Other Description cytoskeletal-associated protein tyrosine phosphatase|protein-tyrosine phosphatase pez|tyrosine-protein phosphatase non-receptor type 14
Swissprots Q5VSI0 Q15678
Accessions ADN23589 EAW93351 Q15678 AF086517 AK056963 AK090596 AK291641 BAF84330 AK298120 BAG60402 AW192897 BC017300 AAH17300 BC101754 AAI01755 BC104803 AAI04804 BX538306 DA738908 HG493205 HQ116786 ADN23590 X82676 CAA57993 XR_247032 NM_005401 NP_005392
Function Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell- matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial- mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor. {ECO:0000269|PubMed:10934049, ECO:0000269|PubMed:12808048, ECO:0000269|PubMed:17893246, ECO:0000269|PubMed:20826270, ECO:0000269|PubMed:22233626, ECO:0000269|PubMed:22525271, ECO:0000269|PubMed:22948661}.
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus. Note=Translocation into the nucleus is associated with induction of cell proliferation. Partially colocalized with actin filaments at the plasma membrane.
Tissue Specificity Ubiquitous.

PTPN14 (D5T6Y) Rabbit mAb - 13808 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D5T6Y
Western blot analysis of extracts from various cell lines using PTPN14 (D5T6Y) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).

Pez (F-12) - sc-373766 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Pez (F-12): sc-373766. Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta tissue showing cytoplasmic staining of trophoblastic cells.

Pez (H-67) - sc-68384 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Pez (H-67): sc-68384. Western blot analysis of Pez expression in K-562 whole cell lysate.

Pez (G-20) - sc-66616 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pez (G-20): sc-66616. Western blot analysis of Pez expression in HUV-EC-C whole cell lysate.

Pez (E-19) - sc-66615 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pez (E-19): sc-66615. Western blot analysis of Pez expression in HUV-EC-C whole cell lysate.

Pez (C-16) - sc-66614 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pez (C-16): sc-66614. Western blot analysis of Pez expression in SHP-77 whole cell lysate.

Anti-PTPD2 antibody - ab126114 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PTPD2 antibody (ab126114) at 1/1000 dilutionLane 1 : A549 cell lysateLane 2 : HCT116 cell lysateLysates/proteins at 30 µg per lane.

Anti-PTPD2 antibody - ab123729 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PTPD2 antibody (ab123729) at 1/100 dilution + Mouse bladder tissue lysates at 35 µg

Anti-PTPD2 antibody - N-terminal - ab139709 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-PTPD2 antibody - N-terminal (ab139709) at 1/500 dilution + HeLa total cell extract

Anti-PTPN14 / PEZ Antibody (aa493-509) - LS-C3167 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PTPN14 / PEZ Antibody (aa329-900) - LS-C75229 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PTPN14 / PEZ Antibody (aa861-890, AP) - LS-C267538 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPN14 / PEZ Antibody (aa861-890, APC) - LS-C267541 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPN14 / PEZ Antibody (aa861-890, Biotin) - LS-C267542 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPN14 / PEZ Antibody (aa861-890, Azide-free, HRP) - LS-C267544 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPN14 / PEZ Antibody (aa861-890, FITC) - LS-C267543 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPN14 / PEZ Antibody (aa861-890, PE) - LS-C267545 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPN14 / PEZ Antibody (aa861-890) - LS-C330036 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPN14 / PEZ Antibody (N-Terminus) - LS-C205815 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PTPN14 / PEZ antibody Western Blot of Mouse Testis. Antibody dilution: 1 ug/ml.

Anti-PTPN14 / PEZ Antibody (aa861-890) - LS-C162302 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PTPN14 Antibody western blot of mouse bladder tissue lysates (35 ug/lane). The PTPN14 antibody detected the PTPN14 protein (arrow).

PTPN14/PTPD2 Antibody (448701) - MAB4458 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 448701
Western blot shows lysates of DU145 human prostate carcinoma cell line, HT‑29 human colon adenocarcinoma cell line, and HT‑29 human colon adenocarcinoma cell line. PVDF membrane was probed with 1 µg/mL of Human PTPN14 Monoclonal Antibody (Catalog # MAB4458) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for PTPN14 at approximately 135 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

PTPN14/PTPD2 Antibody - NBP2-38712 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PTPN14/PTPD2 Antibody [NBP2-38712] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG

PTPN14/PTPD2 Antibody - NBP2-15070 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PTPD2 Antibody [NBP2-15070] - Sample (30 ug of whole cell lysate) A: 293T 5% SDS PAGE; antibody diluted at 1:1000.

PTPN14/PTPD2 Antibody - NBP2-15069 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PTPD2 Antibody [NBP2-15069] - Sample (30 ug of whole cell lysate) A: A549 B: HCT116 5% SDS PAGE; antibody diluted at 1:1000.

PTPN14/PTPD2 Antibody - NB100-75310 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. (anti-PTPN14)
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