Tpx2

Gene Symbol Tpx2
Entrez Gene 72119
Alt Symbol 2610005B21Rik, DIL2, REPP86, p100
Species Mouse
Gene Type protein-coding
Description TPX2, microtubule-associated protein homolog (Xenopus laevis)
Other Description targeting protein for Xklp2
Swissprots Q6P9S6 Q3U500 A2APB8
Accessions A2APB8 EDL05994 EDL05995 EDL05996 EDL05997 AK011311 BAB27537 AK090101 BAC41092 AK153957 BAE32280 AK167030 AK190284 BC060619 AAH60619 BU148033 BU612544 CA327246 CA558942 CJ163921 CO434548 CV555694 XM_006500213 XP_006500276 XM_006500214 XP_006500277 XM_006500215 XP_006500278 NM_001141975 NP_001135447 NM_001141976 NP_001135448 NM_001141977 NP_001135449 NM_001141978 NP_001135450 NM_028109 NP_082385
Function Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation and protects the phosphorylated residue against dephosphorylation (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:18663142}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:18663142}. Note=During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. Is released from the nucleus in apoptotic cells and is detected on apoptotic microtubules (By similarity). {ECO:0000250}.

Recombinant Mouse Targeting protein for Xklp2(Tpx2) - CSB-YP024139MO CSB-EP024139MO CSB-BP024139MO CSB-MP024139MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Targeting protein for Xklp2 (Tpx2), Recombinant Protein - MBS950595 from MyBioSource

Category Protein
Prices $1,555.00, $1,555.00, $1,785.00, $1,785.00, $2,680.00, $2,680.00, $3,125.00, $3,125.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

Recombinant Mouse TPX2 Protein - TPX2-17278M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse
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