ARF6

Gene Symbol	ARF6
Entrez Gene	382
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	ADP-ribosylation factor 6
Other Description	-
Swissprots	P62330 Q6FGZ2
Accessions	AAP50257 EAW65740 P62330 AF047432 AAC39877 AF493885 AAM12599 AK313790 BAG36527 AL117621 AL121163 BC002952 BC008918 AAH08918 BC030291 BM838197 BT019868 AAV38671 CR541939 CAG46737 CR541964 CAG46762 DA217686 M57763 AAA90928 NM_001663 NP_001654
Function	GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. May also modulate vesicle budding and uncoating within the Golgi apparatus. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. {ECO:0000269|PubMed:11266366, ECO:0000269|PubMed:14978216, ECO:0000269|PubMed:16099990, ECO:0000269|PubMed:16737952, ECO:0000269|PubMed:18400762, ECO:0000269|PubMed:21170023, ECO:0000269|PubMed:7589240}.
Subcellular Location	Golgi apparatus. Cell membrane; Lipid- anchor. Endosome membrane; Lipid-anchor. Recycling endosome membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Cell projection, filopodium membrane; Lipid-anchor. Midbody {ECO:0000250}. Cytoplasm {ECO:0000250}. Cleavage furrow {ECO:0000250}. Note=Distributed throughout the cytoplasm during metaphase. Transiently detected at the ingressing cleavage furrow during mitotic cytokinesis. Recruited to the midbody at later stages of cytokinesis; this requires interaction with KIF23 (By similarity). Recruited to the cell membrane in association with CYTH2 and ARL4C. Colocalizes with DAB2IP at the plasma membrane and endocytic vesicles. {ECO:0000250}.
Tissue Specificity	Ubiquitous, with higher levels in heart, substantia nigra, and kidney. {ECO:0000269|PubMed:14659046}.
Top Pathways	Fc gamma R-mediated phagocytosis, Endocytosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ADP-ribosylation factor 6 (ARF6), Human, ELISA Kit - CSB-EL001996HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

ADP-ribosylation factor 6 (ARF6), Human, ELISA Kit - E01A1025 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 50-1000pg/ml

ADP-ribosylation factor 6 (ARF6), Human, ELISA Kit - E01A1628 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

ADP-ribosylation factor 6 (ARF6), ELISA Kit - MBS7208149 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ADP-ribosylation factor 6 (ARF6), ELISA Kit - MBS7200740 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ADP-ribosylation factor 6 (ARF6), ELISA Kit - MBS7243504 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ADP ribosylation factor 6 (ARF6), ELISA Kit - MBS7221883 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ADP-ribosylation factor 6, ELISA Kit - MBS915887 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human ARF6 is typically less than 3.9 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 15.6 pg/ml -1000 pg/ml.

ADP-ribosylation factor 6 (ARF6), ELISA Kit - MBS7234054 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ADP-ribosylation factor 6 (ARF6), ELISA Kit - MBS7228423 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ADP-ribosylation factor 6 (ARF6), ELISA Kit - MBS7201295 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ADP-ribosylation factor 6 (ARF6), ELISA Kit - MBS7216931 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ADP-ribosylation factor 6 (ARF6), ELISA Kit - MBS7232078 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ADP-ribosylation factor 6 (ARF6), ELISA Kit - MBS7240819 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ADP-ribosylation factor 6 (ARF6), ELISA Kit - MBS7236223 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ADP-ribosylation factor 6 (ARF6), ELISA Kit - MBS7228885 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human ADP-ribosylation factor 6(ARF6) ELISA kit - CSB-EL001996HU from Cusabio Category ELISA Kit Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

Human ADP-ribosylation factor 6 (ARF6) ELISA Kit - EKC32501 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

Human ARF6 ELISA Kit - E001006 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human ARF6 is typically less than 3.9 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean

ARF6 ELISA Kit (Human) (OKCA00603) - OKCA00603 from Aviva Systems Biology Category ELISA Kit Prices $590.00 Sizes 96 wells Sensitivity 3.9 pg/mL Range 15.6 pg/mL-1,000 pg/mL

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