PPIP5K2

Gene Symbol PPIP5K2
Entrez Gene 23262
Alt Symbol HISPPD1, IP7K2, VIP2
Species Human
Gene Type protein-coding
Description diphosphoinositol pentakisphosphate kinase 2
Other Description VIP1 homolog 2|histidine acid phosphatase domain-containing protein 1|inositol heptaphosphate kinase 2|inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2|insP6 and PP-IP5 kinase 2
Swissprots A6NGS8 Q8TB50 O43314 A1NI53
Accessions EAW49076 EAW49077 EAW49078 EAW49079 O43314 AB007893 BAA24863 AK025159 AK027116 AK294787 BAG57912 BC024591 AAH24591 DB298507 DC404725 XM_005271935 XP_005271992 XM_005271936 XP_005271993 XM_005271938 XP_005271995 XM_005277534 XP_005277591 XM_005277535 XP_005277592 XM_005277536 XP_005277593 XM_005277538 XP_005277595 XM_005277539 XP_005277596 XM_005277541 XP_005277598 XM_006714576 XP_006714639 XM_006714577 XP_006714640 XM_011543290 XP_011541592 NR_074081 NM_001276277 NP_001263206 NM_001281471 NP_001268400 NM_015216 NP_056031
Function Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis- diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates inositol hexakisphosphate (InsP6) at positions 1 or 3 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4. Alternatively, phosphorylates at position 1 or 3 PP-InsP5, produced by IP6Ks from InsP6, to produce (PP)2-InsP4. {ECO:0000269|PubMed:17690096, ECO:0000269|PubMed:17702752}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:17690096}.

Human PPIP5K2 protein fragment - ab127203 from Abcam

Category Protein
Source E. coli
Species Human

PPIP5K2 / HISPPD1 Antibody Blocking Peptide - LS-E19932 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PPIP5K2 / HISPPD1 Antibody Blocking Peptide - LS-E19931 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

HISPPD1 Blocking Peptide - 33R-8626 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

HISPPD1 fusion protein - Ag23414 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50
Source E. coli -derived, PET28a
Species Human

HISPPD1 fusion protein - Ag23374 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human Inositol hexakisphosphate and diphosphoinositol-pentakisphosph - CSB-YP010373HU CSB-EP010373HU CSB-BP010373HU CSB-MP010373HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

HISPPD1 Recombinant Protein Antigen - NBP2-38368PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

HISPPD1 Recombinant Protein Antigen - NBP1-91990PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

PPIP5K2 Peptide, Human - M34GP12210H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (PPIP5K2), partial, Recombinant Protein - MBS1221904 from MyBioSource

Category Protein
Prices $1,135.00, $1,135.00, $1,365.00, $1,365.00, $1,770.00, $1,770.00, $2,230.00, $2,230.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
Search more