PPIP5K2

Gene Symbol PPIP5K2
Entrez Gene 23262
Alt Symbol HISPPD1, IP7K2, VIP2
Species Human
Gene Type protein-coding
Description diphosphoinositol pentakisphosphate kinase 2
Other Description VIP1 homolog 2|histidine acid phosphatase domain-containing protein 1|inositol heptaphosphate kinase 2|inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2|insP6 and PP-IP5 kinase 2
Swissprots A6NGS8 Q8TB50 O43314 A1NI53
Accessions EAW49076 EAW49077 EAW49078 EAW49079 O43314 AB007893 BAA24863 AK025159 AK027116 AK294787 BAG57912 BC024591 AAH24591 DB298507 DC404725 XM_005271935 XP_005271992 XM_005271936 XP_005271993 XM_005271938 XP_005271995 XM_005277534 XP_005277591 XM_005277535 XP_005277592 XM_005277536 XP_005277593 XM_005277538 XP_005277595 XM_005277539 XP_005277596 XM_005277541 XP_005277598 XM_006714576 XP_006714639 XM_006714577 XP_006714640 XM_011543290 XP_011541592 NR_074081 NM_001276277 NP_001263206 NM_001281471 NP_001268400 NM_015216 NP_056031
Function Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis- diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates inositol hexakisphosphate (InsP6) at positions 1 or 3 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4. Alternatively, phosphorylates at position 1 or 3 PP-InsP5, produced by IP6Ks from InsP6, to produce (PP)2-InsP4. {ECO:0000269|PubMed:17690096, ECO:0000269|PubMed:17702752}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:17690096}.

HISPPD1 CRISPR/Cas9 KO Plasmid (h) - sc-408840 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HISPPD1 HDR Plasmid (h) - sc-408840-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HISPPD1 Double Nickase Plasmid (h) - sc-408840-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HISPPD1 Double Nickase Plasmid (h2) - sc-408840-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HISPPD1 CRISPR Activation Plasmid (h) - sc-408840-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HISPPD1 CRISPR Activation Plasmid (h2) - sc-408840-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HISPPD1 Lentiviral Activation Particles (h) - sc-408840-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HISPPD1 Lentiviral Activation Particles (h2) - sc-408840-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HISPPD1 siRNA (h) - sc-91902 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HISPPD1 shRNA Plasmid (h) - sc-91902-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HISPPD1 shRNA (h) Lentiviral Particles - sc-91902-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU078461 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® Human Phosphatase - SIHP0242 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0243 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0241 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN17238 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17238 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PPIP5K2 siRNA (Human) - CRH8133 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HISPPD1 RNAi - H00023262-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human PPIP5K2 (NM_015216.2) - SHH380764 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human HISPPD1(NM_015216.2) - SHH121439 from Creative biogene

Category siRNA
Species Reactivities Human

Human PPIP5K2 siRNA - orb268635 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PPIP5K2 shRNA Plasmid (Human) - CHH8133 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PPIP5K2 miRNA 3'UTR clone - MiUTR1H-04512 from Creative biogene

Species Reactivities Human
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