PPIP5K2

Gene Symbol PPIP5K2
Entrez Gene 23262
Alt Symbol HISPPD1, IP7K2, VIP2
Species Human
Gene Type protein-coding
Description diphosphoinositol pentakisphosphate kinase 2
Other Description VIP1 homolog 2|histidine acid phosphatase domain-containing protein 1|inositol heptaphosphate kinase 2|inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2|insP6 and PP-IP5 kinase 2
Swissprots A6NGS8 Q8TB50 O43314 A1NI53
Accessions EAW49076 EAW49077 EAW49078 EAW49079 O43314 AB007893 BAA24863 AK025159 AK027116 AK294787 BAG57912 BC024591 AAH24591 DB298507 DC404725 XM_005271935 XP_005271992 XM_005271936 XP_005271993 XM_005271938 XP_005271995 XM_005277534 XP_005277591 XM_005277535 XP_005277592 XM_005277536 XP_005277593 XM_005277538 XP_005277595 XM_005277539 XP_005277596 XM_005277541 XP_005277598 XM_006714576 XP_006714639 XM_006714577 XP_006714640 XM_011543290 XP_011541592 NR_074081 NM_001276277 NP_001263206 NM_001281471 NP_001268400 NM_015216 NP_056031
Function Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis- diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates inositol hexakisphosphate (InsP6) at positions 1 or 3 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4. Alternatively, phosphorylates at position 1 or 3 PP-InsP5, produced by IP6Ks from InsP6, to produce (PP)2-InsP4. {ECO:0000269|PubMed:17690096, ECO:0000269|PubMed:17702752}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:17690096}.

HISPPD1 (N-14) - sc-168084 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HISPPD1 (N-14): sc-168084. Western blot analysis of HISPPD1 expression in non-transfected: sc-117752 (A) and human HISPPD1 transfected: sc-113677 (B) 293T whole cell lysates.

HISPPD1 (P-12) - sc-168085 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HISPPD1 (P-12): sc-168085. Western blot analysis of HISPPD1 expression in non-transfected: sc-117752 (A) and human HISPPD1 transfected: sc-113677 (B) 293T whole cell lysates.

Anti-PPIP5K2 / HISPPD1 Antibody (aa914-963) - LS-C146105 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PPIP5K2 / HISPPD1 antibody LS-C146105 Western blot of Mouse Thymus lysate. Antibody concentration 1 ug/ml.

Anti-PPIP5K2 / HISPPD1 Antibody (aa611-660) - LS-C102598 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PPIP5K2 / HISPPD1 antibody LS-C102598 Western blot of Transfected 293T cell lysate.

Anti-PPIP5K2 / HISPPD1 Antibody (aa925-975) - LS-C290810 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse PPIP5K2 by Western Blot. Samples: Whole cell lysate (50 ug) from K562, HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-PPIP5K2 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

Anti-PPIP5K2 / HISPPD1 Antibody (aa1-50) - LS-C290807 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HISPPD1 Antibody - NBP2-32155 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HISPPD1 Antibody [NBP2-32155] - Samples: Whole cell lysate (50 ug) from K562, HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-HISPPD1 antibody NBP2-32155 used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

HISPPD1 Antibody - NBP2-38368 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HISPPD1 Antibody - NBP2-16836 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HISPPD1 Antibody [NBP2-16836] - Sample (30 ug of whole cell lysate) A: Raji B: K562 5% SDS PAGE gel, diluted at 1:3000.

HISPPD1 Antibody - NBP1-54642 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HISPPD1 Antibody [NBP1-54642] - Transfected 293T cell lysate, concentration 0.2-1 ug/ml.

HISPPD1 Antibody - NBP1-91990 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: HISPPD1 Antibody [NBP1-91990] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules while strong nuclear positivity in cells in glomeruli.

HISPPD1 Antibody - NBP2-32154 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunoprecipitation: HISPPD1 Antibody [NBP2-32154] - Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-HISPPD1 antibody NBP2-32154 used for IP at 6 ug/mg lysate. For blotting immunoprecipitated HISPPD1 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

Anti-PPIP5K2 (N-terminal) antibody produced in rabbit - SAB2701103 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PPIP5K2 (N-terminal): <B>Cat. No. SAB2701103</B>: Immunohistochemical analysis of paraffin-embedded PC13 xenograft, using HISPPD1 antibody at 1:500 dilution.

Anti-PPIP5K2 antibody produced in rabbit - HPA038442 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HISPPD1: <B>Cat. No. HPA038442</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules while strong nuclear positivity in cells in glomeruli.

Anti-HISPPD1 antibody produced in rabbit - SAB2103219 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HISPPD1, antibody produced in rabbit: <B>Cat. No. SAB2103219</B>: Immunoblotting analysis of HISPPD1 in transfected 293T cell lysate with HISPPD1 anitbody at 1 μg/mL.

HISPPD1 antibody - middle region (ARP55203_P050) - ARP55203_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HISPPD1 antibody [N1N2], N-term - GTX111614 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-HISPPD1 antibody [N1N2], N-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX111614

HISPPD1 antibody - orb77676 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin embedded fetal liver showing cytoplasmic staining using HISPPD1 antibody

HISPPD1 antibody - 70R-2403 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

HISPPD1 Antibody - abx038038 from Abbexa

Host Rabbit
Clonality Polyclonal

HISPPD1 antibody - 26018-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Jurkat cells were subjected to SDS PAGE followed by western blot with 26018-1-AP( HISPPD1 Antibody) at dilution of 1:1000

HISPPD1 Antibody - 26-980 from ProSci

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Antibody used in WB on Transfected 293T at 0.2-1 ug/ml.

HISPPD1 antibody - 26018-1-AP from Proteintech Group

Prices $279.00
Sizes con: 36 μg/150μl
Host Rabbit
Clonality Polyclonal
K-562 cells were subjected to SDS PAGE followed by western blot with 26018-1-AP( HISPPD1 Antibody) at dilution of 1:1000

HISPPD1 Antibody - E305128 from Enogene

Prices $275.00
Sizes 100ug/200ul

HISPPD1 Antibody - GWB-MT739A from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Search more