Gene Symbol | DCLK2 |
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Entrez Gene | 166614 |
Alt Symbol | CL2, CLICK-II, CLICK2, CLIK2, DCAMKL2, DCDC3, DCDC3B, DCK2 |
Species | Human |
Gene Type | protein-coding |
Description | doublecortin-like kinase 2 |
Other Description | CaMK-like CREB regulatory kinase 2|doublecortin and CaM kinase-like 2|doublecortin domain-containing protein 3B|doublecortin-like and CAM kinase-like 2|serine/threonine-protein kinase DCLK2 |
Swissprots | Q8N568 Q8N399 C9J5Q9 Q59GC8 |
Accessions | AAY40983 EAX05001 EAX05002 EAX05003 Q8N568 AB209181 BAD92418 AI419589 AL834498 CAD39156 BC019831 BC032726 BC172430 AAI72430 DA122884 DA201927 DQ890892 ABM81818 DQ893344 ABM84270 DQ896665 ABM87664 XM_005262785 XP_005262842 XM_005262786 XP_005262843 XR_244621 NM_001040260 NP_001035350 NM_001040261 NP_001035351 NR_036614 NM_152619 |
Function | Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules. {ECO:0000250}. |
Tissue Specificity | Expressed in the brain, heart and eyes. {ECO:0000269|PubMed:18075264}. |
DCAMKL2 (T-19) - sc-103450 from Santa Cruz Biotechnology
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DCAMKL2 (H-40) - sc-366788 from Santa Cruz Biotechnology
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DCAMKL2 (S-13) - sc-103449 from Santa Cruz Biotechnology
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Anti-DCAMKL2 antibody - ab106639 from Abcam
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Anti-DCAMKL2 antibody - ab96559 from Abcam
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Anti-DCAMKL2 antibody - ab64852 from Abcam
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Anti-DCAMKL2 antibody - ab58070 from Abcam
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Anti-DCAMKL2 antibody - Aminoterminal end - ab71456 from Abcam
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Anti-DCLK2 / DCAMKL2 Antibody (aa167-196, Biotin) - LS-C234454 from LifeSpan Bioscience
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Anti-DCLK2 / DCAMKL2 Antibody (aa167-196, FITC) - LS-C234453 from LifeSpan Bioscience
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Anti-DCLK2 / DCAMKL2 Antibody (aa167-196, PE) - LS-C234459 from LifeSpan Bioscience
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Anti-DCLK2 / DCAMKL2 Antibody (aa167-196, Azide-free, HRP) - LS-C249802 from LifeSpan Bioscience
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Anti-DCLK2 / DCAMKL2 Antibody (aa167-196, APC) - LS-C234451 from LifeSpan Bioscience
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Anti-DCLK2 / DCAMKL2 Antibody (aa167-196, AP) - LS-C234452 from LifeSpan Bioscience
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Anti-DCLK2 / DCAMKL2 Antibody (aa167-196) - LS-C329460 from LifeSpan Bioscience
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Anti-DCLK2 / DCAMKL2 Antibody (aa348-438) - LS-C307189 from LifeSpan Bioscience
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Anti-DCLK2 / DCAMKL2 Antibody (aa1-50) - LS-C119143 from LifeSpan Bioscience
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Anti-DCLK2 / DCAMKL2 Antibody (aa167-196) - LS-C157680 from LifeSpan Bioscience
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Anti-DCLK2 / DCAMKL2 Antibody (aa187-522) - LS-C185753 from LifeSpan Bioscience
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Anti-DCLK2 / DCAMKL2 Antibody (C-Terminus) IHC-plus⢠- LS-B4635 from LifeSpan Bioscience
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DCAMKL2 Antibody - NBP1-77128 from Novus Biologicals
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DCAMKL2 Antibody - NBP1-85282 from Novus Biologicals
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DCAMKL2 Antibody - H00166614-A01 from Novus Biologicals
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DCAMKL2 Antibody (2A5) - H00166614-M01 from Novus Biologicals
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Anti-DCLK2 antibody produced in rabbit - SAB3500208 from Sigma-Aldrich
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