Gene Symbol | DCLK2 |
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Entrez Gene | 166614 |
Alt Symbol | CL2, CLICK-II, CLICK2, CLIK2, DCAMKL2, DCDC3, DCDC3B, DCK2 |
Species | Human |
Gene Type | protein-coding |
Description | doublecortin-like kinase 2 |
Other Description | CaMK-like CREB regulatory kinase 2|doublecortin and CaM kinase-like 2|doublecortin domain-containing protein 3B|doublecortin-like and CAM kinase-like 2|serine/threonine-protein kinase DCLK2 |
Swissprots | Q8N568 Q8N399 C9J5Q9 Q59GC8 |
Accessions | AAY40983 EAX05001 EAX05002 EAX05003 Q8N568 AB209181 BAD92418 AI419589 AL834498 CAD39156 BC019831 BC032726 BC172430 AAI72430 DA122884 DA201927 DQ890892 ABM81818 DQ893344 ABM84270 DQ896665 ABM87664 XM_005262785 XP_005262842 XM_005262786 XP_005262843 XR_244621 NM_001040260 NP_001035350 NM_001040261 NP_001035351 NR_036614 NM_152619 |
Function | Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules. {ECO:0000250}. |
Tissue Specificity | Expressed in the brain, heart and eyes. {ECO:0000269|PubMed:18075264}. |
Active human DCAMKL2 protein fragment - ab85758 from Abcam
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DCLK2 / DCAMKL2 Antibody Blocking Peptide - LS-E30877 from LifeSpan Bioscience
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DCAMKL2 Peptide - NBP1-77128PEP from Novus Biologicals
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Doublecortin-like kinase 2 - P5533 from Acris Antibodies
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Doublecortin-like kinase 2 Control Peptide - AP30277CP-N from Acris Antibodies
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DCLK2 Peptide - 5635P from ProSci
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Recombinant Human DCAMKL2, GST-tagged, Active - DCAMKL2-293H from Creative Biomart
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Recombinant Human DCLK2 - DCLK2-26989TH from Creative Biomart
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DCAMKL2 Protein, active, 10 µg - 14-716 from EMD Millipore
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DCAMKL2 Protein, active, 250 µg - 14-716M from EMD Millipore
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Recombinant Human Serine/threonine-protein kinase DCLK2(DCLK2) - CSB-YP818706HU CSB-EP818706HU CSB-BP818706HU CSB-MP818706HU from Cusabio
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Doublecortin-like kinase 2 (transcript variant 1) - TP319931 from Acris Antibodies
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Recombinant Human DCLK2/DCAMKL2 GST - CSI13340 from Cell Science
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DCAMKL2 Recombinant Protein Antigen - NBP1-85282PEP from Novus Biologicals
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DCAMKL2-Antibody-N-term-Blocking-Peptide - BP7126a from Abgent, a WuXi AppTec company
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DCLK2-Blocking-Peptide-N-term - BP19971A from Abgent, a WuXi AppTec company
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DCLK2 Peptide, Human - M34GP04085H from Creative Peptides
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DCLK2 Blocking Peptide - CBP5409 from Cohesion Biosciences
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Serine/threonine-protein kinase DCLK2 (DCLK2), Recombinant Protein - MBS1332216 from MyBioSource
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Recombinant Human DCLK2 Protein, MYC/DDK-tagged - DCLK2-1168H from Creative Biomart
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Recombinant Human DCLK2 Protein, GST-tagged - DCLK2-2393H from Creative Biomart
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Recombinant Human DCLK2 Protein, GST-tagged - DCLK2-2394H from Creative Biomart
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