RBM17

Gene Symbol RBM17
Entrez Gene 84991
Alt Symbol SPF45
Species Human
Gene Type protein-coding
Description RNA binding motif protein 17
Other Description 45 kDa-splicing factor|RNA-binding motif protein 17|splicing factor 45|splicing factor 45kDa
Swissprots Q96I25 Q96GY6
Accessions CCQ43786 EAW86405 EAW86406 EAW86407 EAW86408 EAW86409 EAW86410 EAW86411 Q96I25 AA905075 AF542550 AAQ09533 AK021863 AK314952 BAG37457 BC007871 AAH07871 BC009064 AAH09064 BC039322 AAH39322 BX648288 CN291330 CV570433 HQ448221 ADQ32701 NM_001145547 NP_001139019 NM_032905 NP_116294
Function Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia. {ECO:0000269|PubMed:12015979, ECO:0000269|PubMed:17589525}.
Subcellular Location Nucleus {ECO:0000269|PubMed:9731529}.
Top Pathways Spliceosome

RBM17-Over-expression-Lysate - LY13339a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag RBM17 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the gene

RBM17 293T Cell Transient Overexpression Lysate(Denatured) - H00084991-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

RBM17 293 Cell Lysate - 405106 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

RBM17 Overexpression Lysate (Native) - NBL1-15198 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: RBM17 Overexpression Lysate (Adult Normal) [NBL1-15198] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RBM17.

RBM17 Over-expression Lysate Product - GWB-8AE4D0 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

RBM17 Overexpression Lysate (Native) - NBP2-09754 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: RBM17 Overexpression Lysate (Adult Normal) [NBP2-09754] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RBM17.

RBM17 Overexpression Lysate (Denatured) - H00084991-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human RBM17 Knockdown Stable Cell Line - CSC-DC013049 from Creative biogene

Category Cell Line
Species Human
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