Gene Symbol | RBM17 |
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Entrez Gene | 84991 |
Alt Symbol | SPF45 |
Species | Human |
Gene Type | protein-coding |
Description | RNA binding motif protein 17 |
Other Description | 45 kDa-splicing factor|RNA-binding motif protein 17|splicing factor 45|splicing factor 45kDa |
Swissprots | Q96I25 Q96GY6 |
Accessions | CCQ43786 EAW86405 EAW86406 EAW86407 EAW86408 EAW86409 EAW86410 EAW86411 Q96I25 AA905075 AF542550 AAQ09533 AK021863 AK314952 BAG37457 BC007871 AAH07871 BC009064 AAH09064 BC039322 AAH39322 BX648288 CN291330 CV570433 HQ448221 ADQ32701 NM_001145547 NP_001139019 NM_032905 NP_116294 |
Function | Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia. {ECO:0000269|PubMed:12015979, ECO:0000269|PubMed:17589525}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:9731529}. |
Top Pathways | Spliceosome |
Human RBM17 full length protein - ab164727 from Abcam
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Human RBM17 full length protein - ab174402 from Abcam
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Human RBM17 protein fragment - ab164728 from Abcam
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RBM17 Partial Recombinant Protein - H00084991-Q01 from Novus Biologicals
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RBM17 Recombinant Protein - H00084991-P01 from Novus Biologicals
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Recombinant Human RBM17 Protein - NBP2-23445 from Novus Biologicals
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RBM17 protein (His tag) - 80R-3584 from Fitzgerald
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RBM17 / SPF45 (1-401, His-tag) - AR51271PU-N from Acris Antibodies
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RBM17 / SPF45 (1-401, His-tag) - AR51271PU-S from Acris Antibodies
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RBM17 / SPF45 - H00084991-P01-10 from Acris Antibodies
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RBM17 / SPF45 - H00084991-P01-25 from Acris Antibodies
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RBM17 / SPF45 - H00084991-Q01-10 from Acris Antibodies
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RBM17 / SPF45 - H00084991-Q01-25 from Acris Antibodies
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RBM17, 1-401aa, Human, His tag, E.coli - 01-P2451 from ARP American Research Products
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RBM17 fusion protein - ag8278 from Proteintech Group
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RBM17 fusion protein - ag4921 from Proteintech Group
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RBM17 fusion protein - ag0985 from Proteintech Group
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Recombinant human RBM17, His-tagged - RBM17-2451H from Creative Biomart
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Recombinant Human Splicing factor 45(RBM17) - CSB-YP853432HU CSB-EP853432HU CSB-BP853432HU CSB-MP853432HU from Cusabio
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RBM17, 1-401aa, Human, His tag, E.coli - ATGP2451 from ATGen
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RBM17 / SPF45 (transcript variant 1) - TP303232 from Acris Antibodies
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RBM17 Recombinant Protein Antigen - NBP2-38348PEP from Novus Biologicals
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RBM17 Recombinant Protein Antigen - NBP1-81202PEP from Novus Biologicals
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Human RBM17 protein - orb260055 from Biorbyt
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RBM17 Peptide, Human - M34GP13049H from Creative Peptides
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