Gene Symbol | RBM17 |
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Entrez Gene | 84991 |
Alt Symbol | SPF45 |
Species | Human |
Gene Type | protein-coding |
Description | RNA binding motif protein 17 |
Other Description | 45 kDa-splicing factor|RNA-binding motif protein 17|splicing factor 45|splicing factor 45kDa |
Swissprots | Q96I25 Q96GY6 |
Accessions | CCQ43786 EAW86405 EAW86406 EAW86407 EAW86408 EAW86409 EAW86410 EAW86411 Q96I25 AA905075 AF542550 AAQ09533 AK021863 AK314952 BAG37457 BC007871 AAH07871 BC009064 AAH09064 BC039322 AAH39322 BX648288 CN291330 CV570433 HQ448221 ADQ32701 NM_001145547 NP_001139019 NM_032905 NP_116294 |
Function | Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia. {ECO:0000269|PubMed:12015979, ECO:0000269|PubMed:17589525}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:9731529}. |
Top Pathways | Spliceosome |
Human-RBM17-cDNA-Clone - DC02279 from Abgent, a WuXi AppTec company
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RBM17 - MBS1272513 from MyBioSource
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RBM17 - MBS1278967 from MyBioSource
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Human RBM17 cDNA clone(NM_001145547.1) - CDFH016012 from Creative Biomart
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Human RBM17 ORF Clone(NM_001145547.1) - CDCR352942 from Creative Biomart
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Human RBM17 ORF Clone(NM_001145547.1) - CDCR352943 from Creative Biomart
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Human RBM17 ORF Clone(NM_001145547.1) - CDCR352942 from Creative biogene
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Human RBM17 ORF Clone (BC007871) - CDCS408529 from Creative biogene
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Human RBM17 ORF Clone (BC039322) - CDCS408530 from Creative biogene
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Human RBM17 cDNA Clone(NM_001145547.1) - CDFH016012 from Creative biogene
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