Gene Symbol | FH |
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Entrez Gene | 2271 |
Alt Symbol | FMRD, HLRCC, LRCC, MCL, MCUL1 |
Species | Human |
Gene Type | protein-coding |
Description | fumarate hydratase |
Other Description | fumarase|fumarate hydratase, mitochondrial |
Swissprots | B1ANK7 P07954 |
Accessions | AAP57532 EAW70090 EAW70091 EAW70092 EAW70093 P07954 AA669797 AK312415 BAG35325 AW611924 BC003108 AAH03108 BC017444 AAH17444 BT009839 AAP88841 DA129148 EU176358 ABW03809 M15502 AAA52483 U48857 AAD00071 U59309 AAB66354 XM_011544132 XP_011542434 NM_000143 NP_000134 |
Function | Also acts as a tumor suppressor. |
Subcellular Location | Isoform Mitochondrial: Mitochondrion. |
Tissue Specificity | Expressed in red blood cells; underexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology. {ECO:0000269|PubMed:22509282}. |
Top Pathways | Citrate cycle (TCA cycle), Renal cell carcinoma, Pyruvate metabolism, Carbon metabolism |
Fumarase (D9C5) Rabbit mAb - 4567 from Cell Signaling Technology
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fumarate hydratase (H-6) - sc-393992 from Santa Cruz Biotechnology
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fumarate hydratase (H-85) - sc-292752 from Santa Cruz Biotechnology
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fumarate hydratase (J-13) - sc-100743 from Santa Cruz Biotechnology
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fumarate hydratase (S-18) - sc-27994 from Santa Cruz Biotechnology
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Anti-FH antibody - ab191367 from Abcam
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Anti-FH antibody - ab58232 from Abcam
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Anti-FH antibody [EPR11647(2)(B)] - N-terminal - ab184945 from Abcam
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Anti-FH antibody [EPR11648] - ab171948 from Abcam
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Anti-FH antibody [GT7612] - C-terminal - ab184644 from Abcam
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Anti-FH antibody - BSA and Azide free - ab182886 from Abcam
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Anti-FH / Fumarase / MCL Antibody (clone 9G4) IHC-plus⢠- LS-B11781 from LifeSpan Bioscience
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Anti-FH / Fumarase / MCL Antibody (Biotin) - LS-C147421 from LifeSpan Bioscience
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Anti-FH / Fumarase / MCL Antibody - LS-C147422 from LifeSpan Bioscience
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Anti-FH / Fumarase / MCL Antibody - LS-C147420 from LifeSpan Bioscience
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Anti-FH / Fumarase / MCL Antibody - LS-C185049 from LifeSpan Bioscience
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Anti-FH / Fumarase / MCL Antibody - LS-C185050 from LifeSpan Bioscience
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Anti-FH / Fumarase / MCL Antibody (Biotin) - LS-C185051 from LifeSpan Bioscience
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Anti-FH / Fumarase / MCL Antibody (aa106-135, APC) - LS-C214252 from LifeSpan Bioscience
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Anti-FH / Fumarase / MCL Antibody (aa106-135, AP) - LS-C214253 from LifeSpan Bioscience
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Anti-FH / Fumarase / MCL Antibody (aa106-135, FITC) - LS-C214254 from LifeSpan Bioscience
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Anti-FH / Fumarase / MCL Antibody (aa106-135, PE) - LS-C214255 from LifeSpan Bioscience
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Anti-FH / Fumarase / MCL Antibody (aa106-135, Azide-free, HRP) - LS-C214256 from LifeSpan Bioscience
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Anti-FH / Fumarase / MCL Antibody (aa106-135) - LS-C329550 from LifeSpan Bioscience
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Anti-FH / Fumarase / MCL Antibody - LS-C341693 from LifeSpan Bioscience
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