ISG20

Gene Symbol	ISG20
Entrez Gene	3669
Alt Symbol	CD25, HEM45
Species	Human
Gene Type	protein-coding
Description	interferon stimulated exonuclease gene 20kDa
Other Description	estrogen-regulated transcript 45 protein|interferon-stimulated gene 20 kDa protein|promyelocytic leukemia nuclear body-associated protein ISG20
Swissprots	Q96AZ6 O00586 O00441
Accessions	EAX02013 EAX02014 EAX02015 EAX02016 Q96AZ6 AB209639 BAD92876 AK122793 AK307769 AV737297 BC007922 AAH07922 BC016341 AAH16341 BG759382 BI838264 BM691295 BT006952 AAP35598 BX339191 CN265233 CR456942 CAG33223 U88964 AAB53416 X89773 CAA61915 XM_005254899 XP_005254956 XM_006720488 XP_006720551 XM_011521521 XP_011519823 NM_001303233 NP_001290162 NM_001303234 NP_001290163 NM_001303235 NP_001290164 NM_001303236 NP_001290165 NM_001303237 NP_001290166 NM_002201 NP_002192 NR_130134
Function	Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single- stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis. {ECO:0000269|PubMed:11401564, ECO:0000269|PubMed:12594219, ECO:0000269|PubMed:16033969, ECO:0000269|PubMed:21036379}.
Subcellular Location	Nucleus. Nucleus, nucleolus. Cytoplasm. Nucleus, Cajal body.
Tissue Specificity	Highly expressed in peripheral blood leukocytes, spleen, thymus, colon and lung. Up regulated by E2 in estrogen receptor-positive breast cancer lines. {ECO:0000269|PubMed:9235947, ECO:0000269|PubMed:9569007}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ISG20 (D-5) - sc-376665 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

ISG20 (H-50) - sc-66937 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

ISG20 (A-13) - sc-34109 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

ISG20 (M-155) - sc-66938 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-ISG20 antibody - ab154393 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ISG20 antibody - ab50834 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ISG20 antibody - ab55338 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-ISG20 antibody - ab129629 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-ISG20 antibody [EPR8972] - ab166633 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR8972

Anti-ISG20 antibody [EPR8973] - ab157477 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR8973

Anti-HEM45 / ISG20 Antibody (clone 1B2-3C9) - LS-C197547 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1B2-3C9

Anti-HEM45 / ISG20 Antibody (clone 143-13) - LS-C96317 from LifeSpan Bioscience Prices $325.00 Sizes 200 µg Host Mouse Clonality Monoclonal Clone 143-13

Anti-HEM45 / ISG20 Antibody (aa35-84) - LS-C30586 from LifeSpan Bioscience Prices $325.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-HEM45 / ISG20 Antibody (aa28-58, AP) - LS-C215284 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-HEM45 / ISG20 Antibody (aa28-58, APC) - LS-C215285 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-HEM45 / ISG20 Antibody (aa28-58, Biotin) - LS-C215286 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-HEM45 / ISG20 Antibody (aa28-58, FITC) - LS-C215287 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-HEM45 / ISG20 Antibody (aa110-159) - LS-C80323 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-HEM45 / ISG20 Antibody (aa28-58, Azide-free, HRP) - LS-C215288 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-HEM45 / ISG20 Antibody (aa28-58, PE) - LS-C215289 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-HEM45 / ISG20 Antibody - LS-C308529 from LifeSpan Bioscience Prices $455.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-HEM45 / ISG20 Antibody - LS-C310784 from LifeSpan Bioscience Prices $475.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-HEM45 / ISG20 Antibody (aa28-58) - LS-C329696 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-HEM45 / ISG20 Antibody (aa29-58) - LS-C165300 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-HEM45 / ISG20 Antibody - LS-C310783 from LifeSpan Bioscience Prices $475.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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