ISG20

Gene Symbol ISG20
Entrez Gene 3669
Alt Symbol CD25, HEM45
Species Human
Gene Type protein-coding
Description interferon stimulated exonuclease gene 20kDa
Other Description estrogen-regulated transcript 45 protein|interferon-stimulated gene 20 kDa protein|promyelocytic leukemia nuclear body-associated protein ISG20
Swissprots Q96AZ6 O00586 O00441
Accessions EAX02013 EAX02014 EAX02015 EAX02016 Q96AZ6 AB209639 BAD92876 AK122793 AK307769 AV737297 BC007922 AAH07922 BC016341 AAH16341 BG759382 BI838264 BM691295 BT006952 AAP35598 BX339191 CN265233 CR456942 CAG33223 U88964 AAB53416 X89773 CAA61915 XM_005254899 XP_005254956 XM_006720488 XP_006720551 XM_011521521 XP_011519823 NM_001303233 NP_001290162 NM_001303234 NP_001290163 NM_001303235 NP_001290164 NM_001303236 NP_001290165 NM_001303237 NP_001290166 NM_002201 NP_002192 NR_130134
Function Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single- stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis. {ECO:0000269|PubMed:11401564, ECO:0000269|PubMed:12594219, ECO:0000269|PubMed:16033969, ECO:0000269|PubMed:21036379}.
Subcellular Location Nucleus. Nucleus, nucleolus. Cytoplasm. Nucleus, Cajal body.
Tissue Specificity Highly expressed in peripheral blood leukocytes, spleen, thymus, colon and lung. Up regulated by E2 in estrogen receptor-positive breast cancer lines. {ECO:0000269|PubMed:9235947, ECO:0000269|PubMed:9569007}.

ISG20 CRISPR/Cas9 KO Plasmid (h) - sc-406055 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20 HDR Plasmid (h) - sc-406055-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20 Double Nickase Plasmid (h) - sc-406055-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20 Double Nickase Plasmid (h2) - sc-406055-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20 CRISPR Activation Plasmid (h) - sc-406055-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20 CRISPR Activation Plasmid (h2) - sc-406055-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20 Lentiviral Activation Particles (h) - sc-406055-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20 Lentiviral Activation Particles (h2) - sc-406055-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20 siRNA (h) - sc-45248 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ISG20 shRNA Plasmid (h) - sc-45248-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ISG20 shRNA (h) Lentiviral Particles - sc-45248-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ISG20 RNAi - H00003669-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU048351 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10787 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10787 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ISG20 siRNA (Human) - CRH2460 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ISG20 - MBS8234070 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ISG20 (NM_002201.4) - SHH320917 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ISG20(NM_002201.4) - SHL174158 from Creative biogene

Category siRNA
Species Reactivities Human

ISG20 shRNA Plasmid (Human) - CHH2460 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ISG20 miRNA 3'UTR clone - MiUTR1H-05007 from Creative biogene

Species Reactivities Human
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