ISG20

Gene Symbol	ISG20
Entrez Gene	3669
Alt Symbol	CD25, HEM45
Species	Human
Gene Type	protein-coding
Description	interferon stimulated exonuclease gene 20kDa
Other Description	estrogen-regulated transcript 45 protein|interferon-stimulated gene 20 kDa protein|promyelocytic leukemia nuclear body-associated protein ISG20
Swissprots	Q96AZ6 O00586 O00441
Accessions	EAX02013 EAX02014 EAX02015 EAX02016 Q96AZ6 AB209639 BAD92876 AK122793 AK307769 AV737297 BC007922 AAH07922 BC016341 AAH16341 BG759382 BI838264 BM691295 BT006952 AAP35598 BX339191 CN265233 CR456942 CAG33223 U88964 AAB53416 X89773 CAA61915 XM_005254899 XP_005254956 XM_006720488 XP_006720551 XM_011521521 XP_011519823 NM_001303233 NP_001290162 NM_001303234 NP_001290163 NM_001303235 NP_001290164 NM_001303236 NP_001290165 NM_001303237 NP_001290166 NM_002201 NP_002192 NR_130134
Function	Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single- stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis. {ECO:0000269|PubMed:11401564, ECO:0000269|PubMed:12594219, ECO:0000269|PubMed:16033969, ECO:0000269|PubMed:21036379}.
Subcellular Location	Nucleus. Nucleus, nucleolus. Cytoplasm. Nucleus, Cajal body.
Tissue Specificity	Highly expressed in peripheral blood leukocytes, spleen, thymus, colon and lung. Up regulated by E2 in estrogen receptor-positive breast cancer lines. {ECO:0000269|PubMed:9235947, ECO:0000269|PubMed:9569007}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ISG20 full length protein - ab158771 from Abcam Category Protein Source Wheat germ Species Human

Human ISG20 full length protein - ab88203 from Abcam Category Protein Source Saccharomyces cerevisiae Species Human

HEM45 / ISG20 Antibody Blocking Peptide - LS-E4311 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HEM45 / ISG20 Antibody Blocking Peptide - LS-E14723 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HEM45 / ISG20 Antibody Blocking Peptide - LS-E14724 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ISG20 Protein - H00003669-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ISG20-Antibody-Center-Blocking-Peptide - BP16602c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CD25 protein - orb197752 from Biorbyt Category Protein Prices $298.00 Sizes 200 μl Species Human

ISG20 Blocking Peptide - 33R-3179 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ISG20 Blocking Peptide - 33R-9301 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human ISG20 Protein - abx060032 from Abbexa Category Protein Source Yeast Species Human

ISG20 / HEM45 - H00003669-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ISG20 / HEM45 - H00003669-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ISG20 fusion protein - Ag17303 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

ISG20 fusion protein - Ag17454 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

sIL 2R Human - CYPS-292 from NeoScientific Category Protein Prices $65.00, $169.00, $3,380.00 Sizes 5 µg, 25 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human IL-2A Soluble Receptor - BP000171-CYT-285 from Syd Labs Category Protein Prices $160.00, $2,600.00 Sizes 25 µg, 1 mg Source E. coli-derived. Species Human

Recombinant Human ISG20, His-tagged - ISG20-28642TH from Creative Biomart Category Protein

sIL 2R Human - BCA-348 from Reagent Proteins Category Protein Prices $348.00, $3,993.00 Sizes 25.00 µg, 1 mg Source E.coli Species Human

sIL 2R Human, GST - BCA-846 from Reagent Proteins Category Protein Prices $348.00, $2,898.00 Sizes 20.00 µg, 10.00 µg Source E.coli Species Human

Human IL2Ra / CD25 Protein (Fc Tag) - 10165-H02H-50 from Sino Biological Category Protein Source Human Cells Species Human

Human IL2Ra / CD25 Protein (His Tag) - 10165-H08H-50 from Sino Biological Category Protein Source Human Cells Species Human

Human sIL-2Ra (sCD25) Recombinant Protein Carrier-Free - 34-8702 from eBioscience Category Protein Prices $109.00, $239.00, $659.00 Sizes 5 µg, 25 µg, 100 µg Species Human

Recombinant Interleukin 2 Receptor Alpha (IL2Ra) - RPB837Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Interferon-stimulated gene 20 kDa protein(ISG20) - CSB-YP846587HU CSB-EP846587HU CSB-BP846587HU CSB-MP846587HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

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