Gene Symbol | ETS1 |
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Entrez Gene | 2113 |
Alt Symbol | ETS-1, EWSR2, p54 |
Species | Human |
Gene Type | protein-coding |
Description | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
Other Description | Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1|protein C-ets-1|v-ets avian erythroblastosis virus E2 oncogene homolog 1 |
Swissprots | Q16080 P14921 A9UL17 F5GYX9 Q96AC5 Q14278 Q6N087 |
Accessions | AAA52409 EAW67709 EAW67710 EAW67711 EAW67712 P14921 AK001630 AK291840 BAF84529 AK301405 BAG62940 AL832693 AY943926 AAY19514 BC017314 AAH17314 BG035366 BM468663 BP365215 BT019452 AAV38259 BT019453 AAV38260 BX640634 CAE45783 CA407336 CR542254 CAG47050 J04101 AAA52410 S53284 S67063 AAB28747 S87905 X14798 CAA32903 XM_011542649 XP_011540951 XM_011542650 XP_011540952 XM_011542651 XP_011540953 XM_011542652 XP_011540954 NM_001143820 NP_001137292 NM_001162422 NP_001155894 NM_005238 NP_005229 |
Function | Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion. {ECO:0000269|PubMed:10698492, ECO:0000269|PubMed:11909962, ECO:0000269|PubMed:15247905, ECO:0000269|PubMed:15592518}. |
Subcellular Location | Cytoplasm. Nucleus. Note=Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27. |
Tissue Specificity | Highly expressed within lymphoid cells. Isoforms c-ETS-1A and Ets-1 p27 are both detected in all fetal tissues tested, but vary with tissue type in adult tissues. None is detected in brain or kidney. {ECO:0000269|PubMed:19377509, ECO:0000269|PubMed:20378371}. |
Top Pathways | Renal cell carcinoma, HTLV-I infection, Dorso-ventral axis formation |
ETS-1 (D8O8A) Rabbit mAb - 14069 from Cell Signaling Technology
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ETS-1 Antibody - 6258 from Cell Signaling Technology
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Ets-1 (C-4) - sc-55581 from Santa Cruz Biotechnology
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Ets-1 (H-150) - sc-22802 from Santa Cruz Biotechnology
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Ets-1 (N-276) - sc-111 from Santa Cruz Biotechnology
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Ets-1 (C-20) - sc-350 from Santa Cruz Biotechnology
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Ets-1/Ets-2 (C-275) - sc-112 from Santa Cruz Biotechnology
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Ets-1/Ets-2 (D-7) - sc-374509 from Santa Cruz Biotechnology
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Anti-ETS1 (phospho T38) antibody - ab59179 from Abcam
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Anti-ETS1 antibody - ab186844 from Abcam
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Anti-ETS1 antibody - ab59217 from Abcam
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Anti-ETS1 antibody [1G11] - ab10936 from Abcam
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Anti-ETS1 antibody [8A8] - ab96478 from Abcam
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Anti-ETS1 antibody [EPR546(2)] - ab109212 from Abcam
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Anti-ETS1 / ETS-1 Antibody - LS-C310289 from LifeSpan Bioscience
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Anti-ETS1 / ETS-1 Antibody (aa46-74) - LS-C329520 from LifeSpan Bioscience
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Anti-ETS1 / ETS-1 Antibody (aa95-144) - LS-C201211 from LifeSpan Bioscience
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Anti-ETS1 / ETS-1 Antibody (aa151-244) - LS-C311456 from LifeSpan Bioscience
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Anti-ETS1 / ETS-1 Antibody (phospho-Thr38) - LS-C342104 from LifeSpan Bioscience
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Anti-ETS1 / ETS-1 Antibody (Ala32) - LS-C175893 from LifeSpan Bioscience
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Anti-ETS1 / ETS-1 Antibody (clone 10D2) - LS-C109133 from LifeSpan Bioscience
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Anti-ETS1 / ETS-1 Antibody (phospho-Thr38) - LS-C198939 from LifeSpan Bioscience
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Anti-ETS1 / ETS-1 Antibody (clone 2G10) - LS-C197162 from LifeSpan Bioscience
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Anti-ETS1 / ETS-1 Antibody (clone ETS1B8D7) - LS-C342336 from LifeSpan Bioscience
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Anti-ETS1 / ETS-1 Antibody (aa43-70) - LS-C167843 from LifeSpan Bioscience
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