Gene Symbol | NPBWR2 |
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Entrez Gene | 2832 |
Alt Symbol | GPR8 |
Species | Human |
Gene Type | protein-coding |
Description | neuropeptides B/W receptor 2 |
Other Description | G protein-coupled receptor 8|G-protein coupled receptor 8|neuropeptides B/W receptor type 2|opioid-somatostatin-like receptor 8 |
Swissprots | Q9H4K3 Q6NWQ6 P48146 |
Accessions | AAC50198 EAW75161 P48146 BC067481 AAH67481 BC067482 AAH67482 BC067483 AAH67483 HQ447590 ADQ32076 NM_005286 NP_005277 |
Function | Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Detected at high levels in caudate nucleus, hyppocampus and amygdala; at moderate levels in the adult brain, thalamus, parietal cortex, pituitary gland, adrenal gland and lymph nodes. {ECO:0000269|PubMed:12401809}. |
Top Pathways | Neuroactive ligand-receptor interaction |
GPR8 (N-20) - sc-27208 from Santa Cruz Biotechnology
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GPR8 (V-12) - sc-27209 from Santa Cruz Biotechnology
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Anti-GPCR GPR8 antibody - ab133967 from Abcam
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Anti-GPCR GPR8 antibody - C-terminal - ab140874 from Abcam
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Anti-NPBWR2 / GPR8 Antibody (N-Terminus) IHC-plus⢠- LS-A175 from LifeSpan Bioscience
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Anti-NPBWR2 / GPR8 Antibody (Cytoplasmic Domain) IHC-plus⢠- LS-A6636 from LifeSpan Bioscience
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Anti-NPBWR2 / GPR8 Antibody (aa319-333) - LS-C190873 from LifeSpan Bioscience
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Anti-NPBWR2 / GPR8 Antibody (N-Terminus) - LS-C152016 from LifeSpan Bioscience
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GPR8 Antibody - NLS175 from Novus Biologicals
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GPR8 Antibody - NLS6636 from Novus Biologicals
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Anti-NPBWR2 antibody produced in rabbit - SAB2900479 from Sigma-Aldrich
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Anti-NPBWR2 antibody produced in rabbit - SAB2900626 from Sigma-Aldrich
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NPBWR2 Antibody - N-terminal region (ARP65592_P050) - ARP65592_P050 from Aviva Systems Biology
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GPR8 antibody - GTX71641 from GeneTex
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GPR8 antibody [N1], N-term - GTX108161 from GeneTex
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GPR8 antibody [N1C3] - GTX117407 from GeneTex
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Anti -G-Protein Coupled Receptor 8 (GPCR8, GPR8, Neuropeptides B/W Receptor Type 2,NPBWR2) - G8600-12B from USBiological Life Science
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NPBWR2 Antibody (OALA00312) - OALA00312 from Aviva Systems Biology
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NPBWR2 Antibody (OALA01057) - OALA01057 from Aviva Systems Biology
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Rabbit Anti-Human NPBWR2 / GPR8 (Cytoplasmic Domain) - 119-10569 from RayBiotech
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Rabbit Anti-Human NPBWR2 / GPR8 (N-Terminus) - 119-11159 from RayBiotech
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Anti- Neuropeptides B/W receptor type 2 Antibody - GWB-BEC6F0 from Genway Biotech
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Anti- Neuropeptides B/W receptor type 2 Antibody - GWB-5354F7 from Genway Biotech
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Anti-NPBWR2 (cytoplasmic domain) polyclonal antibody - DPABH-02518 from Creative Diagnostics
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Anti-NPBWR2 (aa 18-67) polyclonal antibody - DPABH-25524 from Creative Diagnostics
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