Gene Symbol | NPBWR2 |
---|---|
Entrez Gene | 2832 |
Alt Symbol | GPR8 |
Species | Human |
Gene Type | protein-coding |
Description | neuropeptides B/W receptor 2 |
Other Description | G protein-coupled receptor 8|G-protein coupled receptor 8|neuropeptides B/W receptor type 2|opioid-somatostatin-like receptor 8 |
Swissprots | Q9H4K3 Q6NWQ6 P48146 |
Accessions | AAC50198 EAW75161 P48146 BC067481 AAH67481 BC067482 AAH67482 BC067483 AAH67483 HQ447590 ADQ32076 NM_005286 NP_005277 |
Function | Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Detected at high levels in caudate nucleus, hyppocampus and amygdala; at moderate levels in the adult brain, thalamus, parietal cortex, pituitary gland, adrenal gland and lymph nodes. {ECO:0000269|PubMed:12401809}. |
Top Pathways | Neuroactive ligand-receptor interaction |