| Gene Symbol |
NPBWR2
|
| Entrez Gene |
2832
|
| Alt Symbol |
GPR8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neuropeptides B/W receptor 2
|
| Other Description |
G protein-coupled receptor 8|G-protein coupled receptor 8|neuropeptides B/W receptor type 2|opioid-somatostatin-like receptor 8
|
| Swissprots |
Q9H4K3 Q6NWQ6 P48146
|
| Accessions |
AAC50198 EAW75161 P48146 BC067481 AAH67481 BC067482 AAH67482 BC067483 AAH67483 HQ447590 ADQ32076 NM_005286 NP_005277
|
| Function |
Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Detected at high levels in caudate nucleus, hyppocampus and amygdala; at moderate levels in the adult brain, thalamus, parietal cortex, pituitary gland, adrenal gland and lymph nodes. {ECO:0000269|PubMed:12401809}.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|