Gene Symbol | PYCR2 |
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Entrez Gene | 29920 |
Alt Symbol | P5CR2 |
Species | Human |
Gene Type | protein-coding |
Description | pyrroline-5-carboxylate reductase family, member 2 |
Other Description | P5C reductase 2|pyrroline 5-carboxylate reductase isoform|pyrroline-5-carboxylate reductase 2 |
Swissprots | Q9Y5J4 Q7Z515 A8K798 Q96C36 |
Accessions | EAW69761 EAW69762 EAW69763 EAW69764 EAW69765 Q96C36 AF087859 AAP97169 AF151351 AAD34611 AK001508 BAG50929 AK291913 BAF84602 AL834217 CAD38899 AW166558 BC014868 AAH14868 BC020553 AAH20553 BU538765 HQ447797 ADQ32281 HY044355 HY264354 NM_001271681 NP_001258610 NM_013328 NP_037460 |
Function | Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH. {ECO:0000269|PubMed:2722838, ECO:0000269|PubMed:6894153}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:2722838}. |
Tissue Specificity | Detected in erythrocytes (at protein level). {ECO:0000269|PubMed:2722838, ECO:0000269|PubMed:6894153}. |
Top Pathways | Arginine and proline metabolism, Biosynthesis of amino acids |
Human PYCR2 full length protein - ab162262 from Abcam
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Human PYCR2 full length protein - ab202150 from Abcam
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P5CR2 / PYCR2 Antibody Blocking Peptide - LS-E1264 from LifeSpan Bioscience
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P5CR2 / PYCR2 Antibody Blocking Peptide - LS-E19815 from LifeSpan Bioscience
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PYCR2 Recombinant Protein - H00029920-P01 from Novus Biologicals
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PYCR2-Antibody-Center-Blocking-peptide - BP11852c from Abgent, a WuXi AppTec company
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PYCR2 Blocking Peptide - 33R-5055 from Fitzgerald
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PYCR2 Blocking Peptide - 33R-4866 from Fitzgerald
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PYCR2 protein - 80R-4204 from Fitzgerald
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PYCR2 (1-320, His-tag) - AR51886PU-N from Acris Antibodies
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PYCR2 (1-320, His-tag) - AR51886PU-S from Acris Antibodies
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PYCR2 - H00029920-P01-10 from Acris Antibodies
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PYCR2 - H00029920-P01-25 from Acris Antibodies
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PYCR2 fusion protein - ag10918 from Proteintech Group
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PYCR2 fusion protein - ag10923 from Proteintech Group
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Recombinant Human PYCR2, GST-tagged - PYCR2-2085H from Creative Biomart
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Recombinant Human PYCR2, His-tagged - PYCR2-46H from Creative Biomart
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Pyrroline-5-carboxylate Reductase 2 - CBCRY25 from Creative Biomart
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Recombinant Human Pyrroline-5-carboxylate reductase 2(PYCR2) - CSB-YP822188HU CSB-EP822188HU CSB-BP822188HU CSB-MP822188HU from Cusabio
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PYCR2, 1-320aa, Human, His tag, E.coli - ATGP3066 from ATGen
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PYCR2 - TP304525 from Acris Antibodies
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PYCR2 Recombinant Protein Antigen - NBP2-47318PEP from Novus Biologicals
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PYCR2 Peptide, Human - M34GP12776H from Creative Peptides
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Recombinant Human PYCR2 Protein - NBP2-52069 from Novus Biologicals
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Pyrroline-5-Carboxylate Reductase 2, Human Recombinant - 228-20493-1 from RayBiotech
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