Gene Symbol | PYCR2 |
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Entrez Gene | 29920 |
Alt Symbol | P5CR2 |
Species | Human |
Gene Type | protein-coding |
Description | pyrroline-5-carboxylate reductase family, member 2 |
Other Description | P5C reductase 2|pyrroline 5-carboxylate reductase isoform|pyrroline-5-carboxylate reductase 2 |
Swissprots | Q9Y5J4 Q7Z515 A8K798 Q96C36 |
Accessions | EAW69761 EAW69762 EAW69763 EAW69764 EAW69765 Q96C36 AF087859 AAP97169 AF151351 AAD34611 AK001508 BAG50929 AK291913 BAF84602 AL834217 CAD38899 AW166558 BC014868 AAH14868 BC020553 AAH20553 BU538765 HQ447797 ADQ32281 HY044355 HY264354 NM_001271681 NP_001258610 NM_013328 NP_037460 |
Function | Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH. {ECO:0000269|PubMed:2722838, ECO:0000269|PubMed:6894153}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:2722838}. |
Tissue Specificity | Detected in erythrocytes (at protein level). {ECO:0000269|PubMed:2722838, ECO:0000269|PubMed:6894153}. |
Top Pathways | Arginine and proline metabolism, Biosynthesis of amino acids |
P5CR2 (C-12) - sc-138500 from Santa Cruz Biotechnology
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Anti-PYCR2 antibody - ab185578 from Abcam
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Anti-PYCR2 antibody - ab103535 from Abcam
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Anti-PYCR2 antibody [2F11] - ab117913 from Abcam
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Anti-P5CR2 / PYCR2 Antibody (aa218-267) - LS-C81964 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (C-Terminus) - LS-C81965 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (aa89-116, AP) - LS-C223802 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (aa89-116, APC) - LS-C223803 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (aa89-116, Biotin) - LS-C223804 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (aa89-116, FITC) - LS-C223805 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (aa89-116, Azide-free, HRP) - LS-C223806 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (aa89-116, PE) - LS-C223808 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (aa89-116) - LS-C162338 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (aa96-124) - LS-C324440 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (clone 5B7) - LS-C172407 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (clone 2B11) - LS-C337148 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (clone 4B7) - LS-C337152 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (clone 2A12) - LS-C172414 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (clone 3D1) - LS-C172415 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (clone 4A10) - LS-C115748 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (clone 2A5) - LS-C115757 from LifeSpan Bioscience
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Anti-P5CR2 / PYCR2 Antibody (clone 5C7) - LS-C172491 from LifeSpan Bioscience
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PYCR2 Antibody (3D1) - NBP2-03187 from Novus Biologicals
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PYCR2 Antibody - H00029920-D01P from Novus Biologicals
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Anti-PYCR2 (ab2) antibody produced in rabbit - SAB2101919 from Sigma-Aldrich
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