PYCR2

Gene Symbol	PYCR2
Entrez Gene	29920
Alt Symbol	P5CR2
Species	Human
Gene Type	protein-coding
Description	pyrroline-5-carboxylate reductase family, member 2
Other Description	P5C reductase 2|pyrroline 5-carboxylate reductase isoform|pyrroline-5-carboxylate reductase 2
Swissprots	Q9Y5J4 Q7Z515 A8K798 Q96C36
Accessions	EAW69761 EAW69762 EAW69763 EAW69764 EAW69765 Q96C36 AF087859 AAP97169 AF151351 AAD34611 AK001508 BAG50929 AK291913 BAF84602 AL834217 CAD38899 AW166558 BC014868 AAH14868 BC020553 AAH20553 BU538765 HQ447797 ADQ32281 HY044355 HY264354 NM_001271681 NP_001258610 NM_013328 NP_037460
Function	Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH. {ECO:0000269|PubMed:2722838, ECO:0000269|PubMed:6894153}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:2722838}.
Tissue Specificity	Detected in erythrocytes (at protein level). {ECO:0000269|PubMed:2722838, ECO:0000269|PubMed:6894153}.
Top Pathways	Arginine and proline metabolism, Biosynthesis of amino acids

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

P5CR2 CRISPR/Cas9 KO Plasmid (h) - sc-406048 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

P5CR2 HDR Plasmid (h) - sc-406048-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

P5CR2 Double Nickase Plasmid (h) - sc-406048-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

P5CR2 Double Nickase Plasmid (h2) - sc-406048-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

P5CR2 CRISPR Activation Plasmid (h) - sc-406048-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

P5CR2 CRISPR Activation Plasmid (h2) - sc-406048-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

P5CR2 Lentiviral Activation Particles (h) - sc-406048-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

P5CR2 Lentiviral Activation Particles (h2) - sc-406048-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

P5CR2 siRNA (h) - sc-88660 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

P5CR2 shRNA Plasmid (h) - sc-88660-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

P5CR2 shRNA (h) Lentiviral Particles - sc-88660-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU067031 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17768 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17768 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04713 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr04713

PYCR2 siRNA (Human) - CRH9268 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human PYCR2 (NM_013328.2) - SHH387388 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PYCR2(NM_013328.2) - SHR156008 from Creative biogene Category siRNA Species Reactivities Human

P5CR2 CRISPR/Cas9 KO Plasmid (h2) - sc-406048-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

P5CR2 HDR Plasmid (h2) - sc-406048-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Human PYCR2 siRNA - orb269770 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PYCR2 shRNA Plasmid (Human) - CHH9268 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

PYCR2 miRNA 3'UTR clone - MiUTR1H-08522 from Creative biogene Species Reactivities Human

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