Gene Symbol | ESRP2 |
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Entrez Gene | 80004 |
Alt Symbol | RBM35B |
Species | Human |
Gene Type | protein-coding |
Description | epithelial splicing regulatory protein 2 |
Other Description | RNA binding motif protein 35A|RNA binding motif protein 35B|RNA-binding motif protein 35B|RNA-binding protein 35B |
Swissprots | Q9H6I4 Q9H6T0 Q8N6H8 Q8WZ15 |
Accessions | EAW83214 EAW83215 EAW83216 Q9H6T0 AF289577 AAL55761 AK025571 BAB15173 AK025901 BAB15275 BC030146 AAH30146 BC052309 BC069241 BG721782 BU934976 BU943912 LN680438 CEJ95641 LN680439 CEJ95642 T36047 XM_005256153 XP_005256210 XM_006721273 XP_006721336 XM_011523338 XP_011521640 NM_024939 NP_079215 |
Function | mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. {ECO:0000269|PubMed:19285943}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19285943}. |
Tissue Specificity | Epithelial cell-specific. {ECO:0000269|PubMed:19285943}. |
RBM35B (C-17) - sc-243950 from Santa Cruz Biotechnology
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Anti-ESRP2 antibody - ab113486 from Abcam
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Anti-ESRP2 / RBM35B Antibody (aa61-110) - LS-C31389 from LifeSpan Bioscience
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Anti-ESRP2 / RBM35B Antibody (aa600-649) - LS-C135115 from LifeSpan Bioscience
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Anti-ESRP2 / RBM35B Antibody (aa36-85) - LS-C101883 from LifeSpan Bioscience
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Anti-ESRP2 / RBM35B Antibody (clone 22C5.H7.A6) - LS-C153834 from LifeSpan Bioscience
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Anti-ESRP2 / RBM35B Antibody (N-Terminus) - LS-C170178 from LifeSpan Bioscience
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Anti-ESRP2 / RBM35B Antibody (C-Terminus) - LS-C144331 from LifeSpan Bioscience
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ESRP2 Antibody - NBP2-13972 from Novus Biologicals
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ESRP2 Antibody - NBP2-16375 from Novus Biologicals
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ESRP2 Antibody - H00080004-B01 from Novus Biologicals
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ESRP2 Antibody - H00080004-B01P from Novus Biologicals
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ESRP2 Polyclonal Antibody - bs-13108R from Bioss
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ESRP2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13108R-A350 from Bioss
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ESRP2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13108R-A488 from Bioss
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ESRP2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13108R-A555 from Bioss
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ESRP2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13108R-A647 from Bioss
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ESRP2 Polyclonal Antibody, Cy3 Conjugated - bs-13108R-Cy3 from Bioss
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ESRP2 Polyclonal Antibody, Cy5 Conjugated - bs-13108R-Cy5 from Bioss
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ESRP2 Polyclonal Antibody, Cy5.5 Conjugated - bs-13108R-Cy5.5 from Bioss
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ESRP2 Polyclonal Antibody, Cy7 Conjugated - bs-13108R-Cy7 from Bioss
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ESRP2 Polyclonal Antibody, FITC Conjugated - bs-13108R-FITC from Bioss
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ESRP2 Polyclonal Antibody, Biotin Conjugated - bs-13108R-Biotin from Bioss
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ESRP2 Polyclonal Antibody, HRP Conjugated - bs-13108R-HRP from Bioss
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Anti-RBM35B antibody produced in mouse - SAB1401836 from Sigma-Aldrich
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