MICAL1

Gene Symbol	MICAL1
Entrez Gene	64780
Alt Symbol	MICAL, MICAL-1, NICAL
Species	Human
Gene Type	protein-coding
Description	microtubule associated monooxygenase, calponin and LIM domain containing 1
Other Description	CasL interacting molecule|NEDD9-interacting protein with calponin homology and LIM domains|microtubule associated monoxygenase, calponin and LIM domain containing 1|molecule interacting with CasL protein 1|protein-methionine sulfoxide oxidase MICAL1
Swissprots	B7Z3R5 Q9HAA1 E1P5F0 Q96G47 Q9H7I0 Q7Z633 Q9H6X6 Q9UFF7 Q8IVS9 Q8TDZ2
Accessions	EAW48339 EAW48340 EAW48341 EAW48342 EAW48343 EAW48344 EAW48345 Q8TDZ2 AB048948 BAB86289 AK021999 BAB13949 AK024500 BAB15790 AK025392 BAB15124 AK160384 BAD18727 AK225049 AK296284 BAH12301 AL122098 CAB59266 BC009972 AAH09972 BC036514 BC042144 AAH42144 BC052983 AAH52983 NM_001159291 NP_001152763 NM_001286613 NP_001273542 NM_022765 NP_073602
Function	Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization (Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4. {ECO:0000269|PubMed:18305261, ECO:0000269|PubMed:21864500, ECO:0000305}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton.
Tissue Specificity	Expressed in the thymus, lung, spleen, kidney, testis and hematopoietic cells. {ECO:0000269|PubMed:11827972}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MICAL1 full length protein - ab163878 from Abcam Category Protein Source Wheat germ Species Human

Human MICAL1 protein fragment - ab163879 from Abcam Category Protein Source Wheat germ Species Human

MICAL1 / MICAL Antibody Blocking Peptide - LS-E22622 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MICAL1 Protein - H00064780-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human MICAL1 Protein - H00064780-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MICAL1 Blocking Peptide - 33R-10430 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MICAL1 - H00064780-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

MICAL1 - H00064780-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MICAL1 - H00064780-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MICAL1 fusion protein - Ag6578 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

MICAL1 fusion protein - Ag7674 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human MICAL1, His-tagged - MICAL1-872H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Protein-methionine sulfoxide oxidase MICAL1(MICAL1) ,partial - CSB-YP851555HU CSB-EP851555HU CSB-BP851555HU CSB-MP851555HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MICAL1 - TP308308 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

MICAL1 Recombinant Protein Antigen - NBP2-38154PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MICAL1 Recombinant Protein Antigen - NBP2-38153PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MICAL1 Recombinant Protein Antigen - NBP1-85141PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MICAL1 Peptide, Human - M34GP09505H from Creative Peptides Category Peptide Source Synthetic. Species Human

Protein-methionine sulfoxide oxidase MICAL1 (MICAL1), partial, Recombinant Protein - MBS1405560 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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