MICAL1

Gene Symbol MICAL1
Entrez Gene 64780
Alt Symbol MICAL, MICAL-1, NICAL
Species Human
Gene Type protein-coding
Description microtubule associated monooxygenase, calponin and LIM domain containing 1
Other Description CasL interacting molecule|NEDD9-interacting protein with calponin homology and LIM domains|microtubule associated monoxygenase, calponin and LIM domain containing 1|molecule interacting with CasL protein 1|protein-methionine sulfoxide oxidase MICAL1
Swissprots B7Z3R5 Q9HAA1 E1P5F0 Q96G47 Q9H7I0 Q7Z633 Q9H6X6 Q9UFF7 Q8IVS9 Q8TDZ2
Accessions EAW48339 EAW48340 EAW48341 EAW48342 EAW48343 EAW48344 EAW48345 Q8TDZ2 AB048948 BAB86289 AK021999 BAB13949 AK024500 BAB15790 AK025392 BAB15124 AK160384 BAD18727 AK225049 AK296284 BAH12301 AL122098 CAB59266 BC009972 AAH09972 BC036514 BC042144 AAH42144 BC052983 AAH52983 NM_001159291 NP_001152763 NM_001286613 NP_001273542 NM_022765 NP_073602
Function Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization (Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4. {ECO:0000269|PubMed:18305261, ECO:0000269|PubMed:21864500, ECO:0000305}.
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton.
Tissue Specificity Expressed in the thymus, lung, spleen, kidney, testis and hematopoietic cells. {ECO:0000269|PubMed:11827972}.

MICAL1 CRISPR/Cas9 KO Plasmid (h) - sc-405084 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MICAL1 HDR Plasmid (h) - sc-405084-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MICAL1 Double Nickase Plasmid (h) - sc-405084-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MICAL1 Double Nickase Plasmid (h2) - sc-405084-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MICAL1 CRISPR Activation Plasmid (h) - sc-405084-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MICAL1 CRISPR Activation Plasmid (h2) - sc-405084-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MICAL1 Lentiviral Activation Particles (h) - sc-405084-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MICAL1 Lentiviral Activation Particles (h2) - sc-405084-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MICAL1 siRNA (h) - sc-95537 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MICAL1 shRNA Plasmid (h) - sc-95537-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MICAL1 shRNA (h) Lentiviral Particles - sc-95537-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MICAL1 RNAi - H00064780-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU063141 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13316 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13316 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MICAL1 siRNA (Human) - CRJ2085 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MICAL1 (NM_022765.3) - SHH341827 from Creative biogene

Category siRNA
Species Reactivities Human

Human MICAL1 siRNA - orb272586 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MICAL1 shRNA Plasmid (Human) - CHJ2085 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MICAL1 miRNA 3'UTR clone - MiUTR3H-08993 from Creative biogene

Species Reactivities Human

MICAL1 miRNA 3'UTR clone - MiUTR3H-08994 from Creative biogene

Species Reactivities Human
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