Gene Symbol | GDF2 |
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Entrez Gene | 2658 |
Alt Symbol | BMP-9, BMP9, HHT5 |
Species | Human |
Gene Type | protein-coding |
Description | growth differentiation factor 2 |
Other Description | GDF-2|bone morphogenetic protein 9|growth/differentiation factor 2 |
Swissprots | Q9UK05 Q5VSQ9 Q9Y571 |
Accessions | EAW50660 Q9UK05 AF156891 AAD40309 AF188285 AAD56960 AK314956 BAG37460 BC069643 AAH69643 BC074921 AAH74921 EU446620 ABZ92149 EU446952 ABZ92481 XM_006717761 XP_006717824 NM_016204 NP_057288 |
Function | Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. {ECO:0000269|PubMed:18309101, ECO:0000269|PubMed:22799562, ECO:0000269|PubMed:23300529}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:18309101}. |
BMP-9 (H-3) - sc-514211 from Santa Cruz Biotechnology
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BMP-9 (C-16) - sc-27821 from Santa Cruz Biotechnology
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BMP-9 (F-12) - sc-27820 from Santa Cruz Biotechnology
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BMP-9 (G-23) - sc-130703 from Santa Cruz Biotechnology
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Anti-BMP9 antibody - ab35088 from Abcam
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Anti-BMP9 antibody - ab71809 from Abcam
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Anti-BMP9 antibody [MM0616-16S11] - ab135152 from Abcam
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Anti-BMP9 antibody - C-terminal - ab137567 from Abcam
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Anti-BMP9 antibody - N-terminal - ab135128 from Abcam
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Anti-GDF2 / BMP9 Antibody - LS-C35174 from LifeSpan Bioscience
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Anti-GDF2 / BMP9 Antibody (clone 360107) - LS-C35173 from LifeSpan Bioscience
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Anti-GDF2 / BMP9 Antibody (aa87-98) - LS-C41782 from LifeSpan Bioscience
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Anti-GDF2 / BMP9 Antibody (aa212-223) - LS-C87272 from LifeSpan Bioscience
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Anti-GDF2 / BMP9 Antibody (aa320-429, Biotin) - LS-C300399 from LifeSpan Bioscience
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Anti-GDF2 / BMP9 Antibody (aa22-178, Biotin) - LS-C300400 from LifeSpan Bioscience
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Anti-GDF2 / BMP9 Antibody (aa22-178, FITC) - LS-C303761 from LifeSpan Bioscience
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Anti-GDF2 / BMP9 Antibody (aa320-429, FITC) - LS-C303760 from LifeSpan Bioscience
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Anti-GDF2 / BMP9 Antibody (clone 4D2) - LS-C197286 from LifeSpan Bioscience
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Anti-GDF2 / BMP9 Antibody (aa360-409) - LS-C111641 from LifeSpan Bioscience
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Anti-GDF2 / BMP9 Antibody (aa32-427) - LS-C314826 from LifeSpan Bioscience
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Anti-GDF2 / BMP9 Antibody (aa22-178) - LS-C294349 from LifeSpan Bioscience
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Anti-GDF2 / BMP9 Antibody (aa320-429) - LS-C294350 from LifeSpan Bioscience
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Anti-GDF2 / BMP9 Antibody (aa8-37) - LS-C97992 from LifeSpan Bioscience
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Anti-GDF2 / BMP9 Antibody (aa23-37) IHC-plus™ - LS-B806 from LifeSpan Bioscience
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BMP-9 Antibody (360107) - MAB3209-100 from Novus Biologicals
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