NCEH1

Gene Symbol NCEH1
Entrez Gene 57552
Alt Symbol AADACL1, NCEH
Species Human
Gene Type protein-coding
Description neutral cholesterol ester hydrolase 1
Other Description arylacetamide deacetylase-like 1
Swissprots B7ZAW6 F5H7K4 Q86WZ1 B7Z3A1 B7Z2K4 Q9P2I4 B7Z5U2 Q6PIU2 B7Z906
Accessions EAW78462 Q6PIU2 AB037784 BAA92601 AK294811 BAH11890 AK295641 BAH12137 AK299422 BAH13028 AK304253 BAH14142 AK316431 BAH14802 AL512752 BC028734 AAH28734 BC047588 AAH47588 BG701753 BP395319 DA856205 DB289027 DC306836 NM_001146276 NP_001139748 NM_001146277 NP_001139749 NM_001146278 NP_001139750 NM_020792 NP_065843
Function Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration. {ECO:0000269|PubMed:17052608}.
Subcellular Location Membrane {ECO:0000305|PubMed:12149457}; Single-pass type II membrane protein {ECO:0000305|PubMed:12149457}. Microsome {ECO:0000250}.
Tissue Specificity Expressed in monocyte-derived macrophages. Up- regulated in invasive melanoma and breast carcinoma cell lines. {ECO:0000269|PubMed:12149457, ECO:0000269|PubMed:18782767}.
Top Pathways Bile secretion

AADACL1 (T-14) - sc-99749 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AADACL1 (T-14): sc-99749. Western blot analysis of AADACL1 expression in mouse kidney tissue extract.

AADACL1 (E-14) - sc-99747 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AADACL1 (E-14): sc-99747. Western blot analysis of AADACL1 expression in mouse kidney tissue extract.

Anti-NCEH1 / AADACL1 Antibody (aa403-415) - LS-C61698 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-NCEH1 / AADACL1 Antibody (aa224-273) - LS-C135230 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NCEH1 / AADACL1 antibody LS-C135230 Western blot of Mouse Kidney lysate.

AADACL1 Antibody - NBP1-90294 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

AADACL1 Antibody - NB100-93363 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

AADACL1 Polyclonal Antibody - bs-5162R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NCEH1 antibody produced in rabbit - SAB4301148 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NCEH1 antibody produced in rabbit - HPA026888 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-AADACL1: <B>Cat. No. HPA026888</B>: Immunohistochemical staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells.

NCEH1 Antibody - C-terminal region (ARP49570_P050) - ARP49570_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

AADACL1-Antibody-C-Term - AF2704a from Abgent, a WuXi AppTec company

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

AADACL1 antibody, Internal - GTX48898 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-AADACL1 antibody, Internal used in Western blot. GTX48898

AADACL1 antibody, C-term - GTX88821 from GeneTex

Prices $239.00
Sizes 100 μg
Host Goat
Clonality Polyclonal

Anti -AADACL1 (Arylacetamide deacetylase-like 1) - A3596-01 from USBiological Life Science

Host Goat
Clonality Polyclonal

Anti -AADACL1 (Arylacetamide deacetylase-like 1) (AP) - A3596-01-AP from USBiological Life Science

Host Goat
Clonality Polyclonal

Anti -AADACL1 (Arylacetamide deacetylase-like 1) (APC) - A3596-01-APC from USBiological Life Science

Host Goat
Clonality Polyclonal

Anti -AADACL1 (Arylacetamide deacetylase-like 1) (Biotin) - A3596-01-Biotin from USBiological Life Science

Host Goat
Clonality Polyclonal

Anti -AADACL1 (Arylacetamide deacetylase-like 1) (FITC) - A3596-01-FITC from USBiological Life Science

Host Goat
Clonality Polyclonal

Anti -AADACL1 (Arylacetamide deacetylase-like 1) (HRP) - A3596-01-HRP from USBiological Life Science

Host Goat
Clonality Polyclonal

Anti -AADACL1 (Arylacetamide deacetylase-like 1) (PE) - A3596-01-PE from USBiological Life Science

Host Goat
Clonality Polyclonal

AADACL1 Antibody (OAEB00027) - OAEB00027 from Aviva Systems Biology

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

NCEH antibody (FITC) - orb7305 from Biorbyt

Prices $315.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

NCEH antibody - orb4457 from Biorbyt

Prices $340.00, $425.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

Anti-AADACL1 Antibody - AC21-1449 from Abcore

Prices $359.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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