NCEH1

Gene Symbol	NCEH1
Entrez Gene	57552
Alt Symbol	AADACL1, NCEH
Species	Human
Gene Type	protein-coding
Description	neutral cholesterol ester hydrolase 1
Other Description	arylacetamide deacetylase-like 1
Swissprots	B7ZAW6 F5H7K4 Q86WZ1 B7Z3A1 B7Z2K4 Q9P2I4 B7Z5U2 Q6PIU2 B7Z906
Accessions	EAW78462 Q6PIU2 AB037784 BAA92601 AK294811 BAH11890 AK295641 BAH12137 AK299422 BAH13028 AK304253 BAH14142 AK316431 BAH14802 AL512752 BC028734 AAH28734 BC047588 AAH47588 BG701753 BP395319 DA856205 DB289027 DC306836 NM_001146276 NP_001139748 NM_001146277 NP_001139749 NM_001146278 NP_001139750 NM_020792 NP_065843
Function	Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration. {ECO:0000269|PubMed:17052608}.
Subcellular Location	Membrane {ECO:0000305|PubMed:12149457}; Single-pass type II membrane protein {ECO:0000305|PubMed:12149457}. Microsome {ECO:0000250}.
Tissue Specificity	Expressed in monocyte-derived macrophages. Up- regulated in invasive melanoma and breast carcinoma cell lines. {ECO:0000269|PubMed:12149457, ECO:0000269|PubMed:18782767}.
Top Pathways	Bile secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

AADACL1 protein (His-DHFR tag) - ab127377 from Abcam Category Protein Prices $364.00 Sizes 50 µg Source E. coli Species Human

Human AADACL1 full length protein - ab132863 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human AADACL1 full length protein - ab140583 from Abcam Category Protein Prices $297.00 Sizes 100 µg Source E. coli Species Human

NCEH1 / AADACL1 Antibody Blocking Peptide - LS-E17895 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NCEH1 / AADACL1 Antibody Blocking Peptide - LS-E26613 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AADACL1 Recombinant Protein - H00057552-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human AADACL1 Protein - NBP2-23283 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

AADACL1 blocking peptide - GTX88821-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog

Human NCEH1 protein - orb168904 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E.coli

Aadacl1 Blocking Peptide - 33R-5297 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NCEH1 protein (His tag) - 80R-2706 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

AADACL1 Peptide - AC21-1449-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NCEH1 / AADACL1 (1-275, His-tag) - AR50826PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

NCEH1 / AADACL1 (1-275, His-tag) - AR50826PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

NCEH1 / AADACL1 - H00057552-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NCEH1 / AADACL1 - H00057552-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NCEH1, 1-275aa, Human, His tag, E.coli - 01-P2002 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

AADACL1 Peptide - 46-619P from ProSci Category Peptide

AADACL1 fusion protein - Ag5136 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

AADACL1 fusion protein - ag5932 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

NCEH1 Human - PRPS-1400 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source E.coli. Species Human

Recombinant Human NCEH1, His-tagged - NCEH1-7558H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human NCEH1, His-tagged - NCEH1-9191H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Neutral cholesterol ester hydrolase 1(NCEH1) - CSB-YP740791HU CSB-EP740791HU CSB-BP740791HU CSB-MP740791HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NCEH1, 1-275aa, Human, His tag, E.coli (Denatured) - ATGP2002 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

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