Gene Symbol |
LRIG3
|
Entrez Gene |
121227
|
Alt Symbol |
LIG3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
leucine-rich repeats and immunoglobulin-like domains 3
|
Other Description |
LIG-3|leucine-rich repeats and immunoglobulin-like domains protein 3
|
Swissprots |
Q6UXL7 Q8NC72 Q6UXM1
|
Accessions |
EAW97094 EAW97095 Q6UXM1 AK074921 BAC11295 AK130083 AK292857 BAF85546 AK301162 BAG62752 AL833710 AY358288 AAQ88655 AY358295 AAQ88662 AY505340 AAR98629 BC012380 BC126169 AAI26170 BC126171 AAI26172 BC143960 DA456424 XM_011537893 XP_011536195 NM_001136051 NP_001129523 NM_153377 NP_700356
|
Function |
May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1 (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Detected in cytoplasmic vesicles when coexpressed with ERBB4. {ECO:0000250}.
|
Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:15203213}.
|