Gene Symbol | LRIG3 |
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Entrez Gene | 121227 |
Alt Symbol | LIG3 |
Species | Human |
Gene Type | protein-coding |
Description | leucine-rich repeats and immunoglobulin-like domains 3 |
Other Description | LIG-3|leucine-rich repeats and immunoglobulin-like domains protein 3 |
Swissprots | Q6UXL7 Q8NC72 Q6UXM1 |
Accessions | EAW97094 EAW97095 Q6UXM1 AK074921 BAC11295 AK130083 AK292857 BAF85546 AK301162 BAG62752 AL833710 AY358288 AAQ88655 AY358295 AAQ88662 AY505340 AAR98629 BC012380 BC126169 AAI26170 BC126171 AAI26172 BC143960 DA456424 XM_011537893 XP_011536195 NM_001136051 NP_001129523 NM_153377 NP_700356 |
Function | May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1 (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Detected in cytoplasmic vesicles when coexpressed with ERBB4. {ECO:0000250}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:15203213}. |
Human LRIG3 protein fragment - ab165170 from Abcam
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LIG3 / DNA Ligase III Antibody Blocking Peptide - LS-E3899 from LifeSpan Bioscience
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LIG3 / DNA Ligase III Antibody Blocking Peptide - LS-E19828 from LifeSpan Bioscience
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LIG3 / DNA Ligase III Antibody Blocking Peptide - LS-E19829 from LifeSpan Bioscience
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Recombinant Human DNA Ligase III Protein - H00003980-Q01 from Novus Biologicals
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LRIG3 Partial Recombinant Protein - H00121227-Q01 from Novus Biologicals
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DNA Ligase III Recombinant Protein - H00003980-P01 from Novus Biologicals
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Recombinant Human LRIG3, CF - 3495-LR-050 from R&D Systems
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Lig3 Blocking Peptide - 33R-9302 from Fitzgerald
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LRIG3 - H00121227-Q01-10 from Acris Antibodies
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LRIG3 - H00121227-Q01-25 from Acris Antibodies
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LRIG3 fusion protein - ag19335 from Proteintech Group
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Recombinant Leucine Rich Repeats And Immunoglobulin Like Domains Protein 3 (LRIG3) - RPM770Mu01 from Uscn Life Science Inc.
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Recombinant Human LRIG3 Protein, CF - 3495-LR from R&D Systems
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LIG3 fusion protein - Ag24998 from Proteintech Group
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DNA Ligase III Recombinant Protein Antigen - NBP1-87720PEP from Novus Biologicals
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LRIG3 Recombinant Protein Antigen - NBP1-81877PEP from Novus Biologicals
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LRIG3-Blocking-Peptide-N-Term - BP22023a from Abgent, a WuXi AppTec company
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LIG3 Peptide, Human - M34GP08698H from Creative Peptides
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LRIG3 Peptide, Human - M34GP08847H from Creative Peptides
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LRIG3, Recombinant Protein - MBS637520 from MyBioSource
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Recombinant Human LRIG3 Protein, CF - 3495-LR from Novus Biologicals
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LIG3 fusion protein - Ag24917 from Proteintech Group
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DNA Ligase 3 peptide - orb339419 from Biorbyt
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