LRIG3

Gene Symbol LRIG3
Entrez Gene 121227
Alt Symbol LIG3
Species Human
Gene Type protein-coding
Description leucine-rich repeats and immunoglobulin-like domains 3
Other Description LIG-3|leucine-rich repeats and immunoglobulin-like domains protein 3
Swissprots Q6UXL7 Q8NC72 Q6UXM1
Accessions EAW97094 EAW97095 Q6UXM1 AK074921 BAC11295 AK130083 AK292857 BAF85546 AK301162 BAG62752 AL833710 AY358288 AAQ88655 AY358295 AAQ88662 AY505340 AAR98629 BC012380 BC126169 AAI26170 BC126171 AAI26172 BC143960 DA456424 XM_011537893 XP_011536195 NM_001136051 NP_001129523 NM_153377 NP_700356
Function May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1 (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Detected in cytoplasmic vesicles when coexpressed with ERBB4. {ECO:0000250}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:15203213}.

LRIG3 (H-62) - sc-382110 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LRIG3 (H-62): sc-382110. Western blot analysis of LRIG3 expression in U-251-MG (A) and HeLa (B) whole cell lysates.

Anti-LRIG3 antibody - ab197989 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue labeling LRIG3 with ab197989 at 1/50 dilution.

Anti-LRIG3 antibody - ab57332 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57332 LRIG3 antibody at 1ug/ml.

Anti-LRIG3 antibody - ab183619 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LRIG3 antibody (ab183619) at 1/1000 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLane 3 : HeLa whole cell lysateLane 4 : HepG2 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-LRIG3 Antibody (aa1020-1120) - LS-C308804 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

DNA Ligase III Antibody - NBP1-87720 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DNA Ligase III Antibody [NBP1-87720] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

LRIG3 Antibody (814834) [Unconjugated] - MAB3495 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 814834
Western blot shows lysates of KATO‑III human gastric carcinoma cell line, HEK293T human embryonic kidney cell line, and B16‑F1 mouse melanoma cell line. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human LRIG3 Monoclonal Antibody (Catalog # MAB3495) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for LRIG3 at approximately 160 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

LRIG3 Antibody - H00121227-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: LRIG3 Antibody [H00121227-A01] - Detection of LRIG3 on LRIG3 transfected HEK cells and 3.1 pcDNA (control) in 293-T HEK cells. Image provided by Frank Mercado.

LRIG3 Antibody - NBP1-81877 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: LRIG3 Antibody [NBP1-81877] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

LRIG3 Antibody [Unconjugated] - AF3495 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
LRIG3 was detected in immersion fixed paraffin-embedded sections of human cervical cancer tissue using Goat Anti-Human LRIG3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3495) at 3 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm of cancer cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

LRIG3 Antibody (4D5) - H00121227-M02 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4D5

LRIG3 Antibody (814834) [Allophycocyanin] - FAB3495A from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 814834

LRIG3 Polyclonal Antibody - bs-1846R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-LRIG3 antibody produced in mouse - SAB4200368 from Sigma-Aldrich

Prices $343.50
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone LRG3-3
<B>Immunofluorescence</B><BR/>U87 cells were fixed and permeabilized with 4% Paraformaldehyde and 0.5% Triton<SUP>™</SUP> X-100. Fixed cells were stained with 5 μg/mL Mouse Anti-LRIG3 Clone: LRG3-3 (<B>Cat. No. SAB4200368</B>). The antibody was developed using Goat Anti-Mouse IgG, Cy3<SUP>™</SUP> conjugate. Cells were counterstained with DAPI (blue) to stain nuclei.

Monoclonal Anti-LRIG3 antibody produced in mouse - WH0121227M2 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4D5
<B>Immunoblotting</B><BR/>Monoclonal Anti-LRIG3, <B>Cat. No. WH0121227M2</B> used at the antibody concentration: 1 μg/mL. Specific band of ~37.11 kDa using immunogen protein lysate.

LRIG3 antibody - GTX117929 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-LRIG3 antibody used in Western blot. GTX117929

Human LRIG3 Antibody - AF3495 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
LRIG3 in Human Cervical Cancer Tissue. LRIG3 was detected in immersion fixed paraffin-embedded sections of human cervical cancer tissue using Goat Anti-Human LRIG3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3495) at 3 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008 ) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm of cancer cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections .

Human LRIG3 Affinity Purified Polyclonal Ab, Goat IgG - AF3495-SP from R&D Systems

Host Goat
Clonality Polyclonal

Human LRIG3 APC-conjugated Antibody - FAB3495A from R&D Systems

Prices $349.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 814834
Detection of LRIG3 in KATO‑III Human Cell Line by Flow Cytometry. KATO‑III human gastric carcinoma cell line was stained with Mouse Anti-Human LRIG3 APC‑conjugated Monoclonal Antibody (Catalog # FAB3495A, filled histogram) or isotype control antibody (Catalog # IC0041A , open histogram). View our protocol for Staining Membrane-associated Proteins .

Human LRIG3 Antibody - MAB3495 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 814834
Detection of Human and Mouse LRIG3 by Western Blot. Western blot shows lysates of KATO-III human gastric carcinoma cell line, HEK293T human embryonic kidney cell line, and B16-F1 mouse melanoma cell line. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human LRIG3 Monoclonal Antibody (Catalog # MAB3495) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007 ). A specific band was detected for LRIG3 at approximately 160 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1 .

Human LRIG3 MAb (Clone 814834), Mouse IgG2B - MAB3495-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 814834
Detection of Human and Mouse LRIG3 by Western Blot. Western blot shows lysates of KATO‑III human gastric carcinoma cell line, HEK293T human embryonic kidney cell line, and B16‑F1 mouse melanoma cell line. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human LRIG3 Monoclonal Antibody (Catalog # MAB3495) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for LRIG3 at approximately 160 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Lig3 antibody - 70R-9296 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti -LIG3 (DNA Ligase 3, LIG2, LIG3) - 211761 from USBiological Life Science

Host Rabbit
Clonality Polyclonal
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