KLF15

Gene Symbol KLF15
Entrez Gene 28999
Alt Symbol KKLF
Species Human
Gene Type protein-coding
Description Kruppel-like factor 15
Other Description Krueppel-like factor 15|kidney-enriched Kruppel-like factor|kidney-enriched krueppel-like factor
Swissprots Q9UIH9
Accessions EAW79367 Q9UIH9 AB029254 BAA88561 BC036733 AAH36733 BX649049 DQ890911 ABM81837 DQ894062 ABM84988 XM_005247400 XP_005247457 XM_011512743 XP_011511045 NM_014079 NP_054798
Function Transcriptional regulator that binds to the GA element of the CLCNKA promoter. Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart (By similarity). Is a repressor of CTGF expression, involved in the control of cardiac fibrosis. It is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A and GATA4 (By similarity). Involved in podocyte differentiation (By similarity). Inhibits MYOCD activity. Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation. {ECO:0000250, ECO:0000269|PubMed:18586263, ECO:0000269|PubMed:20375365, ECO:0000269|PubMed:20566642, ECO:0000269|PubMed:23999430}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10982849, ECO:0000269|PubMed:17438289}.
Tissue Specificity Highly expressed in liver, skeletal muscle, and kidney. Expressed in cardiomyocytes. Expression is highly reduced in cardiac tissue of patients with non-ischemic cardiomyopathy and aortic aneurysm, and in glomerular disease. Not expressed in bone marrow or lymphoid tissues. {ECO:0000269|PubMed:10982849, ECO:0000269|PubMed:17438289, ECO:0000269|PubMed:20375365, ECO:0000269|PubMed:22493483}.

Human KLF15 Gene cDNA Clone - orb143987 from Biorbyt

Prices $255.00
Sizes 10 μg
Species Human

Human-KLF15-cDNA-Clone - DC07073 from Abgent, a WuXi AppTec company

Prices $561.60
Sizes 10 µg
Species Human
Accession BC036733

KLF15 - MBS1269585 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC036733

Human KLF15 ORF Clone(NM_014079.3) - CDCL168108 from Creative Biomart

Species Human
Accession NM_014079.3

Human KLF15 ORF Clone (BC036733) - CDCS413493 from Creative biogene

Species Human
Accession Q9UIH9

Human KLF15 ORF clone (BC036733) - CDCB158791 from Creative biogene

Species Human
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