GPSM1

Gene Symbol	GPSM1
Entrez Gene	26086
Alt Symbol	AGS3
Species	Human
Gene Type	protein-coding
Description	G-protein signaling modulator 1
Other Description	G-protein signalling modulator 1 (AGS3-like, C. elegans)|G-protein-signaling modulator 1|activator of G-protein signaling 3
Swissprots	Q9UFS8 Q969T1 Q86SR5 Q86YR5 A9Z1X4 B1B0W3
Accessions	EAW88216 EAW88217 EAW88218 Q86YR5 AL117478 CAB55951 AL545250 AY173053 AAO17260 BC009943 BC009979 AAH09979 BC017257 BC017353 AAH17353 BC048343 AAH48343 BI766024 BQ214873 BU631041 XM_011518498 XP_011516800 NM_001145638 NP_001139110 NM_001145639 NP_001139111 NM_001200003 NP_001186932 NM_015597 NP_056412
Function	Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction. {ECO:0000269|PubMed:11024022, ECO:0000269|PubMed:12642577}.
Subcellular Location	Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Tissue Specificity	Expressed in intestinal cells. {ECO:0000269|PubMed:12642577}.
Top Pathways	Cocaine addiction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GPSM1 full length protein - ab161891 from Abcam Category Protein Source Wheat germ Species Human

Human GPSM1 full length protein - ab161892 from Abcam Category Protein Source Wheat germ Species Human

GPSM1 / AGS3 Antibody Blocking Peptide - LS-E1902 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPSM1 / AGS3 Antibody Blocking Peptide - LS-E23864 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPSM1 Recombinant Protein - H00026086-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human GPSM1 Protein - H00026086-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GPSM1-Antibody-Center-Blocking-peptide - BP12738c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RNASEH2C Protein - GTX109269-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

GPSM1 / AGS3 - H00026086-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

GPSM1 / AGS3 - H00026086-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GPSM1 / AGS3 - H00026086-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

GPSM1 / AGS3 - H00026086-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

GPSM1 / AGS3 - H00026086-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GPSM1 fusion protein - ag18773 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

GPSM1 fusion protein - ag18989 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

GPSM1 fusion protein - Ag2018 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human G-protein-signaling modulator 1(GPSM1) - CSB-YP801266HU CSB-EP801266HU CSB-BP801266HU CSB-MP801266HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

GPSM1 / AGS3 (transcript variant 1) - TP327680 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

GPSM1 Recombinant Protein Antigen - NBP1-91968PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GPSM1 Peptide, Human - M34GP06614H from Creative Peptides Category Peptide Source Synthetic. Species Human

G-protein-signaling modulator 1 (GPSM1), Recombinant Protein - MBS1333899 from MyBioSource Category Protein Prices $1,475.00, $1,475.00, $1,705.00, $1,705.00, $2,520.00, $2,520.00, $2,960.00, $2,960.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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