Gene Symbol | ZNF224 |
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Entrez Gene | 7767 |
Alt Symbol | BMZF-2, BMZF2, KOX22, ZNF255, ZNF27 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger protein 224 |
Other Description | bone marrow zinc finger 2|zinc finger 2, bone marrow|zinc finger protein 233|zinc finger protein 255|zinc finger protein 27 (KOX 22)|zinc finger protein KOX22|zinc finger protein ZNF255 |
Swissprots | Q9Y2P6 P17033 Q86V10 A6NFW9 Q9NZL3 Q9UID9 Q8IZC8 |
Accessions | AAF24968 AAG23845 EAW57250 EAW57251 EAW57252 EAW57253 EAW57254 Q9NZL3 AF067164 AAD32448 AF187990 AAF04106 AK292500 BAF85189 AY148489 AAN61121 BC002889 AAH02889 BC051902 AAH51902 DA245440 EU446733 ABZ92262 X52353 CAA36579 XM_005259221 XP_005259278 NM_013398 NP_037530 |
Function | May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells. {ECO:0000269|PubMed:20587513}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:12239212, ECO:0000269|PubMed:20587513, ECO:0000269|PubMed:23665872}. Note=Colocalizes with DEPDC1A at the nucleus. |
Tissue Specificity | Ubiquitous. Mainly expressed in fetal tissues. {ECO:0000269|PubMed:12239212}. |
ZNF224 (T-15) - sc-132520 from Santa Cruz Biotechnology
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ZNF224 (G-16) - sc-102190 from Santa Cruz Biotechnology
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Anti-ZNF224 antibody - ab33650 from Abcam
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Anti-ZNF224 antibody - ab168669 from Abcam
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Anti-ZNF224 antibody - ab185512 from Abcam
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Anti-ZNF224 antibody - N-terminal - ab173362 from Abcam
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Anti-ZNF224 Antibody (aa127-155) - LS-C157425 from LifeSpan Bioscience
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Anti-ZNF224 Antibody (aa124-173) - LS-C31386 from LifeSpan Bioscience
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Anti-ZNF224 Antibody (aa127-155, AP) - LS-C243078 from LifeSpan Bioscience
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Anti-ZNF224 Antibody (aa127-155, Biotin) - LS-C243079 from LifeSpan Bioscience
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Anti-ZNF224 Antibody (aa127-155, APC) - LS-C243080 from LifeSpan Bioscience
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Anti-ZNF224 Antibody (aa127-155, PE) - LS-C243083 from LifeSpan Bioscience
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Anti-ZNF224 Antibody (aa127-155, FITC) - LS-C243082 from LifeSpan Bioscience
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Anti-ZNF224 Antibody (aa126-155) - LS-C326553 from LifeSpan Bioscience
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Anti-ZNF224 Antibody (aa127-155, Azide-free, HRP) - LS-C247319 from LifeSpan Bioscience
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Anti-ZNF224 Antibody (aa395-444) - LS-C116790 from LifeSpan Bioscience
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Anti-ZNF224 Antibody (aa612-661) - LS-C110083 from LifeSpan Bioscience
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Anti-ZNF224 Antibody (clone 2C12) - LS-C198495 from LifeSpan Bioscience
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ZNF224 Antibody - H00007767-B01 from Novus Biologicals
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ZNF224 Antibody - NBP2-30794 from Novus Biologicals
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ZNF224 Antibody (2C12) - H00007767-M01 from Novus Biologicals
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Monoclonal Anti-ZNF224 antibody produced in mouse - SAB1402971 from Sigma-Aldrich
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Anti-ZNF224 antibody produced in rabbit - AV35872 from Sigma-Aldrich
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Anti-ZNF224 antibody produced in rabbit - SAB2106198 from Sigma-Aldrich
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Anti-ZNF224 antibody produced in rabbit - SAB2102824 from Sigma-Aldrich
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