Gene Symbol | ZNF224 |
---|---|
Entrez Gene | 7767 |
Alt Symbol | BMZF-2, BMZF2, KOX22, ZNF255, ZNF27 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger protein 224 |
Other Description | bone marrow zinc finger 2|zinc finger 2, bone marrow|zinc finger protein 233|zinc finger protein 255|zinc finger protein 27 (KOX 22)|zinc finger protein KOX22|zinc finger protein ZNF255 |
Swissprots | Q9Y2P6 P17033 Q86V10 A6NFW9 Q9NZL3 Q9UID9 Q8IZC8 |
Accessions | AAF24968 AAG23845 EAW57250 EAW57251 EAW57252 EAW57253 EAW57254 Q9NZL3 AF067164 AAD32448 AF187990 AAF04106 AK292500 BAF85189 AY148489 AAN61121 BC002889 AAH02889 BC051902 AAH51902 DA245440 EU446733 ABZ92262 X52353 CAA36579 XM_005259221 XP_005259278 NM_013398 NP_037530 |
Function | May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells. {ECO:0000269|PubMed:20587513}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:12239212, ECO:0000269|PubMed:20587513, ECO:0000269|PubMed:23665872}. Note=Colocalizes with DEPDC1A at the nucleus. |
Tissue Specificity | Ubiquitous. Mainly expressed in fetal tissues. {ECO:0000269|PubMed:12239212}. |
ZNF224 CRISPR/Cas9 KO Plasmid (h) - sc-407529 from Santa Cruz Biotechnology
|
||||||||
ZNF224 HDR Plasmid (h) - sc-407529-HDR from Santa Cruz Biotechnology
|
||||||||
ZNF224 Double Nickase Plasmid (h) - sc-407529-NIC from Santa Cruz Biotechnology
|
||||||||
ZNF224 Double Nickase Plasmid (h2) - sc-407529-NIC-2 from Santa Cruz Biotechnology
|
||||||||
ZNF224 CRISPR Activation Plasmid (h) - sc-407529-ACT from Santa Cruz Biotechnology
|
||||||||
ZNF224 CRISPR Activation Plasmid (h2) - sc-407529-ACT-2 from Santa Cruz Biotechnology
|
||||||||
ZNF224 Lentiviral Activation Particles (h) - sc-407529-LAC from Santa Cruz Biotechnology
|
||||||||
ZNF224 Lentiviral Activation Particles (h2) - sc-407529-LAC-2 from Santa Cruz Biotechnology
|
||||||||
ZNF224 siRNA (h) - sc-97807 from Santa Cruz Biotechnology
|
||||||||
ZNF224 shRNA Plasmid (h) - sc-97807-SH from Santa Cruz Biotechnology
|
||||||||
ZNF224 shRNA (h) Lentiviral Particles - sc-97807-V from Santa Cruz Biotechnology
|
||||||||
ZNF224 RNAi - H00007767-R01 from Novus Biologicals
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN23319 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23319 from Sigma-Aldrich
|
||||||||
ZNF224 siRNA (Human) - CRH5258 from Cohesion Biosciences
|
||||||||
ZNF224 - MBS8207565 from MyBioSource
|
||||||||
shRNA set against Human ZNF224 (NM_013398.2) - SHH453336 from Creative biogene
|
||||||||
ZNF224 shRNA Plasmid (Human) - CHH5258 from Cohesion Biosciences
|
||||||||
ZNF224 miRNA 3'UTR clone - MiUTR4H-TG10175 from Creative biogene
|