Gene Symbol | ZNF224 |
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Entrez Gene | 7767 |
Alt Symbol | BMZF-2, BMZF2, KOX22, ZNF255, ZNF27 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger protein 224 |
Other Description | bone marrow zinc finger 2|zinc finger 2, bone marrow|zinc finger protein 233|zinc finger protein 255|zinc finger protein 27 (KOX 22)|zinc finger protein KOX22|zinc finger protein ZNF255 |
Swissprots | Q9Y2P6 P17033 Q86V10 A6NFW9 Q9NZL3 Q9UID9 Q8IZC8 |
Accessions | AAF24968 AAG23845 EAW57250 EAW57251 EAW57252 EAW57253 EAW57254 Q9NZL3 AF067164 AAD32448 AF187990 AAF04106 AK292500 BAF85189 AY148489 AAN61121 BC002889 AAH02889 BC051902 AAH51902 DA245440 EU446733 ABZ92262 X52353 CAA36579 XM_005259221 XP_005259278 NM_013398 NP_037530 |
Function | May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells. {ECO:0000269|PubMed:20587513}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:12239212, ECO:0000269|PubMed:20587513, ECO:0000269|PubMed:23665872}. Note=Colocalizes with DEPDC1A at the nucleus. |
Tissue Specificity | Ubiquitous. Mainly expressed in fetal tissues. {ECO:0000269|PubMed:12239212}. |
Human ZNF224 protein fragment - ab159883 from Abcam
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ZNF224 Antibody Blocking Peptide - LS-E5233 from LifeSpan Bioscience
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ZNF224 Antibody Blocking Peptide - LS-E21347 from LifeSpan Bioscience
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ZNF224 Antibody Blocking Peptide - LS-E12770 from LifeSpan Bioscience
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ZNF224 Antibody Blocking Peptide - LS-E12769 from LifeSpan Bioscience
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Recombinant Human ZNF224 Protein - H00007767-Q01 from Novus Biologicals
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ZNF224-Antibody-N-term-Blocking-Peptide - BP17677a from Abgent, a WuXi AppTec company
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ZNF224 - H00007767-Q01-10 from Acris Antibodies
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ZNF224 - H00007767-Q01-25 from Acris Antibodies
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Recombinant Human Zinc finger protein 224(ZNF224) - CSB-YP026592HU CSB-EP026592HU CSB-BP026592HU CSB-MP026592HU from Cusabio
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Zinc finger protein 224(ZNF224) , Recombinant Protein - MBS1440202 from MyBioSource
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ZNF224 Peptide, Human - M34GP17927H from Creative Peptides
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ZNF224 Recombinant Protein Antigen - NBP2-30794PEP from Novus Biologicals
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