Gene Symbol | CRYAB |
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Entrez Gene | 1410 |
Alt Symbol | CMD1II, CRYA2, CTPP2, CTRCT16, HEL-S-101, HSPB5, MFM2 |
Species | Human |
Gene Type | protein-coding |
Description | crystallin, alpha B |
Other Description | alpha-crystallin B chain|epididymis secretory protein Li 101|heat shock protein beta-5|heat-shock 20 kD like-protein|renal carcinoma antigen NY-REN-27|rosenthal fiber component |
Swissprots | Q9UC40 Q9UC37 P02511 Q9UC39 B0YIX0 O43416 Q9UC41 Q9UC38 |
Accessions | AAA52104 ACA05949 EAW67162 EAW67163 EAW67164 EAW67165 EAW67166 EAW67167 P02511 AF007162 AAC19161 AK295498 BAG58418 AK314029 BAG36739 AM392549 CAL37427 AM393027 CAL37905 BC007008 AAH07008 BE076509 BF339748 BI548180 BI759672 BM721803 BT006770 AAP35416 DB506606 DQ892517 ABM83443 DQ895729 ABM86655 FJ224314 ACI46006 FJ876064 ACP18852 M24906 AAA60267 S45630 AAB23453 XM_011542608 XP_011540910 XM_011542609 XP_011540911 NM_001289807 NP_001276736 NM_001289808 NP_001276737 NM_001885 NP_001876 |
Function | May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:19464326}. Nucleus {ECO:0000269|PubMed:19464326}. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. |
Tissue Specificity | Lens as well as other tissues. |
Top Pathways | Protein processing in endoplasmic reticulum |
Mouse CRYAB / Alpha B Crystallin ELISA Kit (Sandwich ELISA) - LS-F6602 from LifeSpan Bioscience
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Human CRYAB / Alpha B Crystallin ELISA Kit (Sandwich ELISA) - LS-F6603 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-CRYAB / Alpha B Crystallin (Ser19) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1348 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-CRYAB / Alpha B Crystallin (Ser45) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1349 from LifeSpan Bioscience
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Bovine CRYAB / Alpha B Crystallin ELISA Kit (Sandwich ELISA) - LS-F11221 from LifeSpan Bioscience
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Alpha-crystallin B chain (CRYAB), Human, ELISA Kit - CSB-EL006008HU from ARP American Research Products
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Alpha-crystallin B chain (CRYAB), Human, ELISA Kit - E01A1818 from ARP American Research Products
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Alpha-crystallin B chain, CRYAB, Human, ELISA Kit - E0194h from ARP American Research Products
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Crystallin Alpha B, CRYaB, Human, ELISA Kit - E-EL-H1519 from ARP American Research Products
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Crystallin Alpha B (CRYaB), Human, ELISA Kit - SEC944Hu from ARP American Research Products
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Crystallin Alpha B, CRYaB, Mouse, ELISA Kit - E-EL-M0365 from ARP American Research Products
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Crystallin Alpha B, CRYaB, Rabbit, ELISA Kit - E-EL-RB0205 from ARP American Research Products
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Crystallin Alpha B, CRYaB, Chicken, ELISA Kit - E-EL-Ch0604 from ARP American Research Products
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Crystallin Alpha B, CRYaB, Porcine, ELISA Kit - E-EL-P0926 from ARP American Research Products
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Crystallin Alpha B, CRYaB, Guinea Pig, ELISA Kit - E-EL-GP1137 from ARP American Research Products
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Crystallin Alpha B, CRYaB, Monkey, ELISA Kit - E-EL-MK0030 from ARP American Research Products
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Human CRYAB ELISA Kit - HC0350 from NeoScientific
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Anserine CRYaB ELISA Kit - AC0350 from NeoScientific
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Alpha B Crystallin - MBS806864 from MyBioSource
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Alpha B Crystallin - MBS806881 from MyBioSource
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crystallin, alpha B, ELISA Kit - MBS941861 from MyBioSource
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Alpha B Crystallin ELISA Kit - SKT-123 from StressMarq Bioscience
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Alpha B Crystallin StressXpress® ELISA Kit - SKT-123-480 from StressMarq Bioscience
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CRYAB (Phospho-Ser19) Colorimetric Cell-Based ELISA Kit - CBP1358 from Assay Biotechnology
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CRYAB (Phospho-Ser45) Colorimetric Cell-Based ELISA Kit - CBP1359 from Assay Biotechnology
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