| Gene Symbol |
CRYAB
|
| Entrez Gene |
1410
|
| Alt Symbol |
CMD1II, CRYA2, CTPP2, CTRCT16, HEL-S-101, HSPB5, MFM2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
crystallin, alpha B
|
| Other Description |
alpha-crystallin B chain|epididymis secretory protein Li 101|heat shock protein beta-5|heat-shock 20 kD like-protein|renal carcinoma antigen NY-REN-27|rosenthal fiber component
|
| Swissprots |
Q9UC40 Q9UC37 P02511 Q9UC39 B0YIX0 O43416 Q9UC41 Q9UC38
|
| Accessions |
AAA52104 ACA05949 EAW67162 EAW67163 EAW67164 EAW67165 EAW67166 EAW67167 P02511 AF007162 AAC19161 AK295498 BAG58418 AK314029 BAG36739 AM392549 CAL37427 AM393027 CAL37905 BC007008 AAH07008 BE076509 BF339748 BI548180 BI759672 BM721803 BT006770 AAP35416 DB506606 DQ892517 ABM83443 DQ895729 ABM86655 FJ224314 ACI46006 FJ876064 ACP18852 M24906 AAA60267 S45630 AAB23453 XM_011542608 XP_011540910 XM_011542609 XP_011540911 NM_001289807 NP_001276736 NM_001289808 NP_001276737 NM_001885 NP_001876
|
| Function |
May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:19464326}. Nucleus {ECO:0000269|PubMed:19464326}. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
|
| Tissue Specificity |
Lens as well as other tissues.
|
| Top Pathways |
Protein processing in endoplasmic reticulum
|
