CRYAB

Gene Symbol CRYAB
Entrez Gene 1410
Alt Symbol CMD1II, CRYA2, CTPP2, CTRCT16, HEL-S-101, HSPB5, MFM2
Species Human
Gene Type protein-coding
Description crystallin, alpha B
Other Description alpha-crystallin B chain|epididymis secretory protein Li 101|heat shock protein beta-5|heat-shock 20 kD like-protein|renal carcinoma antigen NY-REN-27|rosenthal fiber component
Swissprots Q9UC40 Q9UC37 P02511 Q9UC39 B0YIX0 O43416 Q9UC41 Q9UC38
Accessions AAA52104 ACA05949 EAW67162 EAW67163 EAW67164 EAW67165 EAW67166 EAW67167 P02511 AF007162 AAC19161 AK295498 BAG58418 AK314029 BAG36739 AM392549 CAL37427 AM393027 CAL37905 BC007008 AAH07008 BE076509 BF339748 BI548180 BI759672 BM721803 BT006770 AAP35416 DB506606 DQ892517 ABM83443 DQ895729 ABM86655 FJ224314 ACI46006 FJ876064 ACP18852 M24906 AAA60267 S45630 AAB23453 XM_011542608 XP_011540910 XM_011542609 XP_011540911 NM_001289807 NP_001276736 NM_001289808 NP_001276737 NM_001885 NP_001876
Function May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:19464326}. Nucleus {ECO:0000269|PubMed:19464326}. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Tissue Specificity Lens as well as other tissues.
Top Pathways Protein processing in endoplasmic reticulum

αB-crystallin CRISPR/Cas9 KO Plasmid (h) - sc-401149 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

αB-crystallin HDR Plasmid (h) - sc-401149-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

αB-crystallin Double Nickase Plasmid (h) - sc-401149-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

αB-crystallin Double Nickase Plasmid (h2) - sc-401149-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

αB-crystallin CRISPR Activation Plasmid (h) - sc-401149-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

αB-crystallin CRISPR Activation Plasmid (h2) - sc-401149-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

αB-crystallin Lentiviral Activation Particles (h) - sc-401149-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

αB-crystallin Lentiviral Activation Particles (h2) - sc-401149-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

αB-crystallin siRNA (h) - sc-40432 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

αB-crystallin shRNA Plasmid (h) - sc-40432-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

αB-crystallin shRNA (h) Lentiviral Particles - sc-40432-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU017321 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6604 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6604 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CRYAB siRNA (Human) - CRH0992 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AlphaB Crystallin/CRYAB RNAi - H00001410-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CRYAB - MBS8239334 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CRYAB (NM_001885.1) - SHH269909 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CRYAB(NM_001885.1) - SHG200841 from Creative biogene

Category siRNA
Species Reactivities Human

Human CRYAB siRNA - orb261494 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CRYAB shRNA Plasmid (Human) - CHH0992 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CRYAB miRNA 3'UTR clone - MiUTR1H-02444 from Creative biogene

Species Reactivities Human
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