SMOX

Gene Symbol	SMOX
Entrez Gene	54498
Alt Symbol	C20orf16, PAO, PAO-1, PAO1, PAOH, PAOH1, SMO
Species	Human
Gene Type	protein-coding
Description	spermine oxidase
Other Description	flavin containing amine oxidase|flavin-containing spermine oxidase|polyamine oxidase 1|putative cyclin G1 interacting protein
Swissprots	Q5TE26 Q9BW38 Q5TE27 D3DVZ4 Q9NPY1 Q9H6H1 Q8IX00 A2A2P5 Q96QT3 A2A2P6 Q6UY28 A8BE87 Q96LC4 Q9NWM0 Q9NP51 Q9NPY2 Q96LC3
Accessions	EAX10457 EAX10458 EAX10459 EAX10460 EAX10461 EAX10462 EAX10463 Q9NWM0 AF519179 AAN77119 AK000753 BAA91360 AK025938 BAB15288 AK127286 AK293485 BAG56974 AL162058 CAB82396 AW136764 AY033889 AAK55763 AY033890 AAK55764 AY033891 AAK55765 AY358104 AAQ88471 BC000669 AAH00669 BG480614 BG679874 EF032141 ABM01872 U61836 XM_011529261 XP_011527563 NM_001270691 NP_001257620 NM_175839 NP_787033 NM_175840 NP_787034 NM_175841 NP_787035 NM_175842 NP_787036
Function	Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.
Subcellular Location	Isoform 6: Cytoplasm. Nucleus.
Tissue Specificity	Widely expressed. Expressed in human tumor cell lines. Isoform 4 is only found in an embryonal kidney cell line. {ECO:0000269|PubMed:18422650}.
Top Pathways	Arginine and proline metabolism, beta-Alanine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PAO (C-3) - sc-166185 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

PAO (H-85) - sc-67018 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

PAO (P-18) - sc-31662 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

PAO (S-14) - sc-31661 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

PAO (H-17) - sc-31660 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-SMOX antibody - ab150971 from Abcam Prices $443.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SMOX / PAO Antibody (aa285-334) - LS-C186785 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Smoothened Antibody - NBP2-24543 from Novus Biologicals Prices $99.00, $299.00 Sizes 25 µg, 100 µg Host Rabbit Clonality Polyclonal

SMOX Antibody - NBP2-13356 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SMOX antibody produced in rabbit - HPA047117 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SMOX (151-165) antibody produced in rabbit - SAB1101510 from Sigma-Aldrich Prices $328.50 Sizes 200 µl Host Rabbit Clonality Polyclonal

SMOX Antibody - C-terminal region (ARP65968_P050) - ARP65968_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

PAOX antibody, C-term - GTX45449 from GeneTex Prices $319.00 Sizes 50 μg Host Rabbit Clonality Polyclonal

PAOX antibody, Internal - GTX45444 from GeneTex Prices $319.00 Sizes 50 μg Host Rabbit Clonality Polyclonal

PAOX antibody, N-term - GTX45451 from GeneTex Prices $319.00 Sizes 50 μg Host Rabbit Clonality Polyclonal

SMO antibody - orb19363 from Biorbyt Prices $408.00 Sizes 100 μg Host Goat Clonality Polyclonal

SMOX antibody - 70R-20406 from Fitzgerald Prices $375.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

PAOX antibody - 70R-2927 from Fitzgerald Prices $345.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

SMO Antibody - abx028740 from Abbexa Host Rabbit Clonality Polyclonal

SMO antibody - 20787-1-AP from Acris Antibodies Prices $270.00 Sizes 150 µl Host Rabbit Clonality Polyclonal

SMO (N-term) antibody - AP32049PU-N from Acris Antibodies Prices $430.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

SMO (1st Extracell. Dom.) antibody - SP4494P from Acris Antibodies Prices $430.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

SMOX antibody - 15052-1-AP from Acris Antibodies Prices $270.00 Sizes 150 µl Host Rabbit Clonality Polyclonal

Goat Anti-Human SMO (C Terminus), (C Terminus) - ER-14-1326 from RayBiotech Host Goat

Goat Anti-Human SMO (internal), (internal region) - ER-14-1327 from RayBiotech Host Goat

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